Abstract Nuclear Factor-Erythroid Factor 2 (Nrf2) is an important transcription factor that
regulates the expression of large number of genes in healthy and disease states. Nrf2 is …

Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic
Parkinson's disease (PD). However, strategies aimed at ameliorating mitochondrial …

Parkinson disease (PD) is a chronic, progressive neurological disease that is associated
with a loss of dopaminergic neurons in the substantia nigra pars compacta of the brain. The …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the
preferential loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction …

Evolving concepts on Parkinson's disease (PD) pathology suggest that α-synuclein (aSYN)
promote dopaminergic neuron dysfunction and death through accumulating in the …

The incidence of neurological diseases, such as Parkinson's disease, Alzheimer's disease
and stroke, is increasing. An increasing number of studies have correlated these diseases …

Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide, mainly affecting the elderly. The disease progresses gradually, with core motor …

As neurons are highly energy-demanding cell, increasing evidence suggests that
mitochondria play a large role in several age-related neurodegenerative diseases. Synaptic …

Lewy Body Disorders (LBDs) lie within the spectrum of age-related neurodegenerative
diseases now frequently categorized as the synucleinopathies. LBDs are considered to be …

The gut microbiota influence neurodevelopment, modulate behavior, and contribute to
neurodegenerative disorders. Several studies have consistently reported a greater …