Modelling posttraumatic stress disorders in animals

B Török, E Sipos, N Pivac, D Zelena - Progress in Neuro …, 2019 - Elsevier
Animal models of posttraumatic stress disorder are useful tools to reveal the neurobiological
basis of the vulnerability to traumatic events, and to develop new treatment strategies, as …

Multiple aspects of inappropriate action of renin–angiotensin, vasopressin, and oxytocin systems in neuropsychiatric and neurodegenerative diseases

E Szczepanska-Sadowska, A Wsol… - Journal of Clinical …, 2022 - mdpi.com
The cardiovascular system and the central nervous system (CNS) closely cooperate in the
regulation of primary vital functions. The autonomic nervous system and several compounds …

Strain differences in the susceptibility to the gut–brain axis and neurobehavioural alterations induced by maternal immune activation in mice

LH Morais, D Felice, AV Golubeva… - Behavioural …, 2018 - journals.lww.com
There is a growing realization that the severity of the core symptoms of autism spectrum
disorders and schizophrenia is associated with gastrointestinal dysfunction. Nonetheless …

Vasopressin as a Possible Link between Sleep-Disturbances and Memory Problems

B Török, J Varga, D Zelena - International Journal of Molecular Sciences, 2022 - mdpi.com
Normal biological rhythms, including sleep, are very important for a healthy life and their
disturbance may induce—among other issues—memory impairment, which is a key problem …

Depressive-and anxiety-like behaviors and stress-related neuronal activation in vasopressin-deficient female Brattleboro rats

A Fodor, KB Kovács, D Balázsfi, B Klausz, O Pintér… - Physiology & …, 2016 - Elsevier
Vasopressin can contribute to the development of stress-related psychiatric disorders,
anxiety and depression. Although these disturbances are more common in females, most of …

Enhanced innate fear and altered stress axis regulation in VGluT3 knockout mice

D Balázsfi, A Fodor, B Török, S Ferenczi, KJ Kovács… - Stress, 2018 - Taylor & Francis
Glutamatergic neurons, characterized by vesicular glutamate transporters (VGluT1-3)
provide the main excitation in the brain. Their disturbances have been linked to various …

Zebrafish models of epigenetic regulation of CNS functions

AM Lakstygal, MS de Abreu, AV Kalueff - Brain research bulletin, 2018 - Elsevier
Epigenetic regulation has become a key focus of neuroscience and biopsychiatry,
implicating DNA methylation, histone modification and other epigenetic mechanisms in …

Investigation of social, affective, and locomotor behavior of adolescent Brattleboro rats reveals a link between vasopressin's actions on arousal and social behavior

KC Schatz, RF Kyne, SL Parmeter, MJ Paul - Hormones and behavior, 2018 - Elsevier
Arginine vasopressin (AVP) has recently been implicated in juvenile and adolescent social
development. How AVP influences social development, however, is not understood …

Application of animal experimental models in the research of schizophrenia

P Wang, M Li, A Zhao, J Ma - American Journal of Medical …, 2021 - Wiley Online Library
Schizophrenia is a relatively common but serious mental illness that results in a heavy
burden to patients, their families, and society. The disease can be triggered by multiple …

Epigenetic modulation of vasopressin expression in health and disease

B Török, CL Fazekas, A Szabó, D Zelena - International Journal of …, 2021 - mdpi.com
Vasopressin is a ubiquitous molecule playing an important role in a wide range of
physiological processes thereby implicated in the pathomechanism of many disorders. Its …