People with epilepsy—in particular, late-onset epilepsy of unknown aetiology—have an
elevated risk of dementia, and seizures have been detected in the early stages of Alzheimer …

Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …

Amyloid-β (Aβ) 1-40 and 1-42 peptides are key mediators of synaptic and cognitive
dysfunction in Alzheimer's disease (AD). Whereas in AD, Aβ is found to act as a pro …

What happens precociously to the brain destined to develop Alzheimer's Disease (AD) still
remains to be elucidated and this is one reason why effective AD treatments are missing …

One third of humans are infected lifelong with the brain-dwelling, protozoan parasite,
Toxoplasma gondii. Approximately fifteen million of these have congenital toxoplasmosis …

Alzheimer's Disease (AD) and epilepsy are common neurological diseases. The prevalence
of epilepsy in AD patients is higher than in healthy subjects, but identifying the reasons for …

Epilepsy and Alzheimer's disease (AD) incidence increases with age. There are reciprocal
relationships between epilepsy and AD. Epilepsy is a risk factor for AD and, in turn, AD is an …

Although amyloid pathology plays a role in epilepsy, little is known about the relationship
between beta amyloid and progression to Alzheimer's disease (AD) among patients with late …

Glutamate is the brain's main excitatory neurotransmitter. Glutamatergic neurons primarily
compose basic neuronal networks, especially in the cortex. An imbalance of excitatory and …

Increasing evidence coming from both experimental and humans' studies strongly suggest
the existence of a link between epilepsy, in particular temporal lobe epilepsy (TLE), and …