Mental disorders are a significant cause of disability worldwide. They profoundly affect
individuals' well-being and impose a substantial financial burden on societies and …

Successful drug discovery is like finding oases of safety and efficacy in chemical and
biological deserts. Screens in disease models, and other decision tools used in drug …

Social behavior is naturally occurring in vertebrate species, which holds a strong
evolutionary component and is crucial for the normal development and survival of …

In light of the hotly discussed 'reproducibility crisis', a rethinking of current methodologies
appears essential. Implementing multi-laboratory designs has been shown to enhance the …

Translational neuroscience bridges insights from specific mechanisms in rodents to complex
functions in humans and is key to advance our general understanding of central nervous …

The replicability of research results has been a cause of increasing concern to the scientific
community. The long-held belief that experimental standardization begets replicability has …

Predictive models are essential for advancing knowledge of brain disorders. High variation
in study outcomes hampers progress. To address the validity of predictive models, we …

Simple Summary Environmental enrichment has been widely studied with laboratory
rodents, but there is no consensus regarding what counts as enrichment or what it should …

Discussions about a replicability crisis in science have been driven by the normative claim
that all of science should be replicable and the empirical claim that most of it isn't. Recently …

Failure to reproduce results from some scientific studies has raised awareness of the critical
need for reproducibility in translational studies. Macroscopic and microscopic examination is …