Patient-derived xenograft models of pancreatic cancer: overview and comparison with other types of models

PL Garcia, AL Miller, KJ Yoon - Cancers, 2020 - mdpi.com
Pancreatic cancer (PC) is anticipated to be second only to lung cancer as the leading cause
of cancer-related deaths in the United States by 2030. Surgery remains the only potentially …

[HTML][HTML] The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment

C Hayes, CL Donohoe, M Davern, NE Donlon - Cancer letters, 2021 - Elsevier
The tumour microenvironment is of critical importance in cancer development and
progression and includes the surrounding stromal and immune cells, extracellular matrix …

Treatment of central nervous system tumors on combination MR-linear accelerators: review of current practice and future directions

JM Bryant, A Doniparthi, J Weygand, R Cruz-Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary Magnetic resonance imaging (MRI) has several advantages over
computerized tomography (CT) in the treatment planning of central nervous system (CNS) …

Metabolic rewiring and stemness: a critical attribute of pancreatic cancer progression

AO Ogunleye, RK Nimmakayala, SK Batra… - Stem Cells, 2023 - academic.oup.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive diseases with a
poor 5-year survival rate. PDAC cells rely on various metabolic pathways to fuel their …

Stereotactic magnetic resonance-guided adaptive and non-adaptive radiotherapy on combination MR-linear accelerators: current practice and future directions

JM Bryant, J Weygand, E Keit, R Cruz-Chamorro… - Cancers, 2023 - mdpi.com
Simple Summary Stereotactic body radiotherapy (SBRT) is an effective radiation therapy
technique that heavily relies upon daily image guidance to achieve the necessary precision …

[PDF][PDF] RETRACTED: hsa_circ_001653 Implicates in the Development of Pancreatic Ductal Adenocarcinoma by Regulating MicroRNA-377-Mediated HOXC6 Axis

H Shi, H Li, T Zhen, Y Dong, X Pei, X Zhang - Molecular Therapy-Nucleic …, 2020 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive pancreatic cancer
with poor survival rate. Circular RNAs (circRNAs) signatures have been identified in some …

Deuterium MRSI characterizations of glucose metabolism in orthotopic pancreatic cancer mouse models

S Markovic, T Roussel, L Agemy, K Sasson… - NMR in …, 2021 - Wiley Online Library
Detecting and mapping metabolism in tissues represents a major step in detecting,
characterizing, treating and understanding cancers. Recently introduced deuterium …

Simple Esterification of [1-13C]-Alpha-Ketoglutarate Enhances Membrane Permeability and Allows for Noninvasive Tracing of Glutamate and Glutamine Production

JE AbuSalim, K Yamamoto, N Miura… - ACS chemical …, 2021 - ACS Publications
Alpha-ketoglutarate (α-KG) is a key metabolite and signaling molecule in cancer cells, but
the low permeability of α-KG limits the study of α-KG mediated effects in vivo. Recently, cell …

[HTML][HTML] Hyperpolarized magnetic resonance and artificial intelligence: Frontiers of imaging in pancreatic cancer

JS Enriquez, Y Chu, S Pudakalakatti… - JMIR Medical …, 2021 - medinform.jmir.org
Background: There is an unmet need for noninvasive imaging markers that can help identify
the aggressive subtype (s) of pancreatic ductal adenocarcinoma (PDAC) at diagnosis and at …

Hyperpolarized 13C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma

JW Gordon, HY Chen, T Nickles, PM Lee… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer‐
related death in the United States. However, early response assessment using the current …