Survivin is the smallest member of the Inhibitor of apoptosis (IAP) family of proteins, involved
in inhibition of apoptosis and regulation of cell cycle. These functional attributes make …

Survivin is the smallest member of the inhibitor of apoptosis protein family, which has key
roles in regulating cell division and inhibiting apoptosis by blocking caspase activation …

Inhibitors of apoptosis (IAPs) are a family of proteins that play a significant role in the control
of programmed cell death (PCD). PCD is essential to maintain healthy cell turnover within …

Inhibitor of apoptosis (IAP) family comprises a group of endogenous proteins that function as
main regulators of caspase activity and cell death. They are considered the main culprits in …

In a previous study, we demonstrated that Tanshinone IIA effectively inhibits CRC
angiogenesis in vivo, but the underlying mechanisms were not elucidated. In this report, we …

The development of cancer vaccines has been intensively pursued over the past 50 years
with modest success. However, recent advancements in the fields of genetics, molecular …

The sequence of events associated with the development of gastric cancer has been
described as “the gastric precancerous cascade”. This cascade is a dynamic process that …

Inflammatory activation and intestinal flora imbalance play an essential role in the
development and progression of colorectal cancer (CRC). Berberine (BBR) has attracted …

Cancer-associated fibroblasts (CAFs) play a critical role in the coevolution of breast tumor
cells and their microenvironment by modifying cellular compartments and regulating cancer …

Hypoxia is a persistent physiological feature of many different solid tumors and a key driver
of malignancy, and in recent years, it has been recognized as an important target for cancer …