Exosome-derived microRNAs of human milk and their effects on infant health and development

BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …

Genetics, epigenetics and transgenerational transmission of obesity in children

N Panera, C Mandato, A Crudele… - Frontiers in …, 2022 - frontiersin.org
Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …

Immunomodulatory properties of human breast milk: microRNA contents and potential epigenetic effects

MMM Hatmal, MAI Al-Hatamleh, AN Olaimat, W Alshaer… - Biomedicines, 2022 - mdpi.com
Infants who are exclusively breastfed in the first six months of age receive adequate
nutrients, achieving optimal immune protection and growth. In addition to the known …

Exercised breastmilk: a kick-start to prevent childhood obesity?

T Moholdt, KI Stanford - Trends in Endocrinology & Metabolism, 2024 - cell.com
Exercise has systemic health benefits through effects on multiple tissues, with intertissue
communication. Recent studies indicate that exercise may improve breastmilk composition …

Potential epigenetic effects of human milk on infants' neurodevelopment

G Gialeli, O Panagopoulou, G Liosis, T Siahanidou - Nutrients, 2023 - mdpi.com
The advantages of human milk feeding, especially in preterm babies, are well recognized.
Infants' feeding with breast milk lowers the likelihood of developing a diverse range of non …

Milk exosomal microRNAs: postnatal promoters of β cell proliferation but potential inducers of β cell de-differentiation in adult life

BC Melnik, G Schmitz - International Journal of Molecular Sciences, 2022 - mdpi.com
Pancreatic β cell expansion and functional maturation during the birth-to-weaning period is
driven by epigenetic programs primarily triggered by growth factors, hormones, and nutrients …

Synergistic Effects of Milk-Derived Exosomes and Galactose on α-Synuclein Pathology in Parkinson's Disease and Type 2 Diabetes Mellitus

BC Melnik - International Journal of Molecular Sciences, 2021 - mdpi.com
Epidemiological studies associate milk consumption with an increased risk of Parkinson's
disease (PD) and type 2 diabetes mellitus (T2D). PD is an α-synucleinopathy associated …

Lifetime impact of cow's milk on overactivation of mTORC1: From fetal to childhood overgrowth, acne, diabetes, cancers, and neurodegeneration

BC Melnik - Biomolecules, 2021 - mdpi.com
The consumption of cow's milk is a part of the basic nutritional habits of Western
industrialized countries. Recent epidemiological studies associate the intake of cow's milk …

Breastfeeding and allergy effect modified by genetic, environmental, dietary, and immunological factors

H Danielewicz - Nutrients, 2022 - mdpi.com
Breastfeeding (BF) is the most natural mode of nutrition. Its beneficial effect has been
revealed in terms of both the neonatal period and those of lifelong effects. However, as for …

Pasteurized non-fermented cow's milk but not fermented milk is a promoter of mTORC1-driven aging and increased mortality

BC Melnik, G Schmitz - Ageing Research Reviews, 2021 - Elsevier
Recent epidemiological studies in Sweden, a country with traditionally high milk
consumption, revealed that the intake of non-fermented pasteurized milk increased all …