Mock circulatory loops used for testing cardiac assist devices: A review of computational and experimental models

F Cappon, T Wu, T Papaioannou, X Du… - … Journal of Artificial …, 2021 - journals.sagepub.com
Heart failure is a major health risk, and with limited availability of donor organs, there is an
increasing need for developing cardiac assist devices (CADs). Mock circulatory loops (MCL) …

A versatile hybrid mock circulation for hydraulic investigations of active and passive cardiovascular implants

A Petrou, M Granegger, M Meboldt, MS Daners - Asaio Journal, 2019 - journals.lww.com
During the development process of active or passive cardiovascular implants, such as
ventricular assist devices or vascular grafts, extensive in-vitro testing is required. The aim of …

Nonlinear control of a hybrid pneumo‐hydraulic mock circuit of the cardiovascular system

A Alhajyounis, Y Aydoğan, A Canbaş, E Kulakoğlu… - 2024 - Wiley Online Library
Hybrid cardiovascular mock circuits (HMC), designed for dynamic testing of Ventricular
Assist Devices (VAD), offer physiologic accuracy by sequestering model complexity in silico …

A hybrid experimental-computational modeling framework for cardiovascular device testing

E Kung, M Farahmand, A Gupta - Journal of …, 2019 - asmedigitalcollection.asme.org
Significant advances in biomedical science often leverage powerful computational and
experimental modeling platforms. We present a framework named physiology simulation …

The need for hybrid modeling in analysis of cardiovascular and respiratory support

K Zielinski, M Darowski, M Kozarski… - … International Journal of …, 2016 - journals.sagepub.com
The analysis of the efficiency and optimum use of cardiovascular and respiratory support
systems is of great importance in research and development as well as in clinical practice …

Control of a pediatric pulsatile ventricular assist device: a hybrid cardiovascular model study

G Ferrari, A Di Molfetta, K Zieliński, L Fresiello… - Artificial …, 2017 - Wiley Online Library
The aim of this work is to study pediatric pneumatic ventricle (PVAD) performance, versus
VAD rate (VADR) and native heart rate (HR) ratio Rr (VADR/HR). The study uses a hybrid …

Modeling and simulation of speed selection on left ventricular assist devices

AT Tzallas, NS Katertsidis, EC Karvounis… - Computers in biology …, 2014 - Elsevier
The control problem for LVADs is to set pump speed such that cardiac output and pressure
perfusion are within acceptable physiological ranges. However, current technology of …

[HTML][HTML] The hybrid (physical-computational) cardiovascular simulator to study valvular diseases

R Pasledni, M Kozarski, JK Mizerski, M Darowski… - Journal of …, 2024 - Elsevier
To better understand the impact of valvular heart disease (VHD) on the hemodynamics of
the circulatory system, investigations can be carried out using a model of the cardiovascular …

An algorithm for coupling multibranch in vitro experiment to numerical physiology simulation for a hybrid cardiovascular model

E Mirzaei, M Farahmand, E Kung - International Journal for …, 2020 - Wiley Online Library
The hybrid cardiovascular modeling approach integrates an in vitro experiment with a
computational lumped‐parameter simulation, enabling direct physical testing of medical …

Berlin Heart EXCOR Ventricular Assist Device: Multilayer membrane rupture in a pediatric patient

A Di Molfetta, S Filippelli, G Ferrari, A Secinaro… - The Annals of Thoracic …, 2016 - Elsevier
A 2-year-old child was implanted with an Berlin Heart EXCOR Ventricular Assist Device
(Berlin Heart, Berlin, Germany) as a bridge to heart transplantation for idiopathic dilated …