Background Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disease
affecting multiple body systems with wide variability in presentation. In 2013, Pediatric …

As is known to all, glioma, a global difficult problem, has a high malignant degree, high
recurrence rate and poor prognosis. We analyzed and summarized signal pathway of the …

The aim of this EMINENTS prospective, single-center, open-label, single-arm study was to
evaluate the cumulative efficacy and safety of reduced doses of everolimus (maintenance …

Renal Angiomyolipoma - StatPearls - NCBI Bookshelf US flag An official website of the United
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Abstract The 2016 World Health Organization (WHO) classification of primary central
nervous system (CNS) tumors includes numerous uncommon (representing≤ 1% of tumors) …

Tuberous sclerosis complex (TSC) is a dominantly inherited disease caused by
hyperactivation of the mTORC1 pathway and characterized by the development of …

Objective: Subependymal Giant Cell Astrocytomas (SEGAs) are slow-growing glioneuronal
tumors typically found around the ventricles of the brain, particularly near the foramen of …

Background and objective Tuberous sclerosis (TS) is a condition whose manifestations in
childhood have been extensively described, but whose presentation in adults is less well …

Objective: To assess the safety and efficacy of low-dose everolimus maintenance therapy for
tuberous sclerosis complex-related renal angiomyolipoma (TSC-RAML) patients that had …

Influence of cyclosporine and everolimus on the main mycophe... : Medicine Influence of
cyclosporine and everolimus on the main mycophenolate mofetil pharmacokinetic parameters …