Runs of homozygosity: current knowledge and applications in livestock

E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

Mesenchymal stem cells in preclinical cancer cytotherapy: a systematic review

I Christodoulou, M Goulielmaki, M Devetzi… - Stem Cell Research & …, 2018 - Springer
Mesenchymal stem cells (MSC) comprise a heterogeneous population of rapidly
proliferating cells that can be isolated from adult (eg, bone marrow, adipose tissue) as well …

The distribution of runs of homozygosity and selection signatures in six commercial meat sheep breeds

DC Purfield, S McParland, E Wall, DP Berry - PloS one, 2017 - journals.plos.org
Domestication and the subsequent selection of animals for either economic or
morphological features can leave a variety of imprints on the genome of a population …

Inbreeding and runs of homozygosity before and after genomic selection in North American Holstein cattle

M Forutan, S Ansari Mahyari, C Baes, N Melzer… - BMC genomics, 2018 - Springer
Background While autozygosity as a consequence of selection is well understood, there is
limited information on the ability of different methods to measure true inbreeding. In the …

Genome-wide selection signatures detection in Shanghai Holstein cattle population identified genes related to adaption, health and reproduction traits

D Liu, Z Chen, W Zhao, L Guo, H Sun, K Zhu, G Liu… - BMC genomics, 2021 - Springer
Background Over several decades, a wide range of natural and artificial selection events in
response to subtropical environments, intensive pasture and intensive feedlot systems have …

Genome-Wide Runs of Homozygosity Revealed Selection Signatures in Bos indicus

SP Dixit, S Singh, I Ganguly, AK Bhatia… - Frontiers in …, 2020 - frontiersin.org
Genome-wide runs of homozygosity (ROH) are suitable for understanding population
history, calculating genomic inbreeding, deciphering genetic architecture of complex traits …

Invited review: Reproductive and genomic technologies to optimize breeding strategies for genetic progress in dairy cattle

A Fleming, EA Abdalla, C Maltecca… - Archives Animal …, 2018 - aab.copernicus.org
Dairy cattle breeders have exploited technological advances that have emerged in the past
in regards to reproduction and genomics. The implementation of such technologies in …

[HTML][HTML] Genome-wide mapping and estimation of inbreeding depression of semen quality traits in a cattle population

M Ferenčaković, J Sölkner, M Kapš, I Curik - Journal of Dairy Science, 2017 - Elsevier
Inbreeding depression is known to affect quantitative traits such as male fertility and sperm
quality, but the genetic basis for these associations is poorly understood. Most studies have …

A comprehensive analysis of runs of homozygosity of eleven cattle breeds representing different production types

T Szmatoła, A Gurgul, I Jasielczuk, T Ząbek… - Animals, 2019 - mdpi.com
Simple Summary Runs of homozygosity (ROH) regions are known to be common in the
genomes of cattle and have become a subject of interest of various research in recent years …

Runs of homozygosity analysis of South African sheep breeds from various production systems investigated using OvineSNP50k data

EF Dzomba, M Chimonyo, R Pierneef, FC Muchadeyi - BMC genomics, 2021 - Springer
Background Population history, production system and within-breed selection pressure
impacts the genome architecture resulting in reduced genetic diversity and increased …