Heterogeneity in gastric cancer: from pure morphology to molecular classifications

I Gullo, F Carneiro, C Oliveira, GM Almeida - Pathobiology, 2018 - karger.com
Gastric cancer (GC) represents a global health concern. Despite advances in prevention,
diagnosis, and therapy, GC is still the third leading cause of cancer mortality worldwide, with …

Molecular alterations in gastric preneoplastic lesions and early gastric cancer

S Battista, MR Ambrosio, F Limarzi, G Gallo… - International journal of …, 2021 - mdpi.com
Prognosis of gastric cancer is dramatically improved by early diagnosis. Correa's cascade
correlates the expression of some molecular markers with the progression of preneoplastic …

CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence

K Hirata, H Suzuki, H Imaeda, J Matsuzaki… - British journal of …, 2013 - nature.com
Background: Multiple early gastric cancers (EGCs) may develop in 6–14% of patients even
after achieving curative endoscopic submucosal dissection (ESD); however, a useful …

Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma

XL Li, Y Eishi, YQ Bai, H Sakai… - International …, 2004 - spandidos-publications.com
Abstract SOX2, a SRY-related HMG box protein, is thought to be an important transcription
factor during organogenesis, including the stomach although the expression and function …

Pyloric gland adenoma: a clinico-pathological analysis of 90 cases

M Vieth, R Kushima, F Borchard, M Stolte - Virchows Archiv, 2003 - Springer
Background Pyloric gland adenoma is a rarely described neoplasia of the gastric mucosa.
Recent publications have shown that similar lesions are also found in the gallbladder, the …

Gastric and intestinal claudin expression at the invasive front of gastric carcinoma

Y Matsuda, S Semba, J Ueda, T Fuku, T Hasuo… - Cancer …, 2007 - Wiley Online Library
Like gastric and intestinal mucins, the tight junction proteins called claudins can be used to
determine the differentiation of gastric mucosa. We investigated the expression of claudins …

[HTML][HTML] Microsatellite instability status in gastric cancer: a reappraisal of its clinical significance and relationship with mucin phenotypes

JY Kim, NR Shin, A Kim, HJ Lee, W Park… - Korean journal of …, 2013 - ncbi.nlm.nih.gov
Background Gastric cancers with microsatellite instabilities (MSI) have been reported to be
associated with favorable prognosis. However, the significance of the effect of MSI on the …

Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background

Y Tajima, K Yamazaki, R Makino, N Nishino… - Clinical Cancer …, 2006 - AACR
Purpose: Gastric and intestinal phenotypic cell markers are expressed in gastric carcinomas,
irrespective of their histologic type. In the present study, we determined the clinicopathologic …

Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia

A Srivastava, GH Kim, M Mino-Kenudson… - The American journal …, 2008 - journals.lww.com
Gastric epithelial dysplasia (GED) can be morphologically categorized into adenomatous (or
intestinal) and foveolar (or gastric) types. Although limited genetic differences have been …

[HTML][HTML] Genetic alterations in gastric adenomas of intestinal and foveolar phenotypes

SC Abraham, SJ Park, JH Lee, L Mugartegui, TT Wu - Modern pathology, 2003 - Elsevier
Gastric adenomas are unusual neoplasms that can constitute one of the direct precursors to
gastric adenocarcinoma. Most gastric adenomas are comprised of polypoid projections of …