Current updates on computer aided protein modeling and designing
Determination of the three dimensional (3D) structure of a protein can provide important
details about its biological functions and mechanism of action. However, despite their …
details about its biological functions and mechanism of action. However, despite their …
Calcium/calmodulin-dependent protein kinase IV: A multifunctional enzyme and potential therapeutic target
The calcium/calmodulin-dependent protein kinase IV (CAMKIV) belongs to the
serine/threonine protein kinase family, and is primarily involved in transcriptional regulation …
serine/threonine protein kinase family, and is primarily involved in transcriptional regulation …
Identification of plant-based hexokinase 2 inhibitors: Combined molecular docking and dynamics simulation studies
Cancer cells ferment glucose, even under aerobic conditions, following a phenomenon
known as the 'Warburg effect.'Hexokinase 2 (HK2) catalyzes the crucial step of …
known as the 'Warburg effect.'Hexokinase 2 (HK2) catalyzes the crucial step of …
Evidence of vanillin binding to CAMKIV explains the anti-cancer mechanism in human hepatic carcinoma and neuroblastoma cells
Human calcium/calmodulin-dependent protein kinase IV (CAMKIV) is a member of Ser/Thr
kinase family, and is associated with different types of cancer and neurodegenerative …
kinase family, and is associated with different types of cancer and neurodegenerative …
[HTML][HTML] Functional Annotation of Conserved Hypothetical Proteins from Haemophilus influenzae Rd KW20
M Shahbaaz, MD ImtaiyazHassan, F Ahmad - PloS one, 2013 - journals.plos.org
Haemophilus influenzae is a Gram negative bacterium that belongs to the family
Pasteurellaceae, causes bacteremia, pneumonia and acute bacterial meningitis in infants …
Pasteurellaceae, causes bacteremia, pneumonia and acute bacterial meningitis in infants …
Identification of sphingosine kinase-1 inhibitors from bioactive natural products targeting cancer therapy
Sphingosine kinase 1 (SphK1) is an oncogenic lipid kinase that catalyzes the formation of
sphingosine-1-phosphate via phosphorylation of sphingosine and known to play a crucial …
sphingosine-1-phosphate via phosphorylation of sphingosine and known to play a crucial …
Curcumin specifically binds to the human calcium–calmodulin-dependent protein kinase IV: Fluorescence and molecular dynamics simulation studies
Calcium–calmodulin-dependent protein kinase IV (CAMK4) plays significant role in the
regulation of calcium-dependent gene expression, and thus, it is involved in varieties of …
regulation of calcium-dependent gene expression, and thus, it is involved in varieties of …
Biological evaluation of p-toluene sulphonylhydrazone as carbonic anhydrase IX inhibitors: An approach to fight hypoxia-induced tumors
To find potential inhibitors of human carbonic anhydrase IX (CAIX), we have successfully
deigned, synthesized and characterized three p-toluene sulphonylhydrazone derivatives (1 …
deigned, synthesized and characterized three p-toluene sulphonylhydrazone derivatives (1 …
Chitinase from Thermomyces lanuginosus SSBP and its biotechnological applications
Chitinases are ubiquitous class of extracellular enzymes, which have gained attention in the
past few years due to their wide biotechnological applications. The effectiveness of …
past few years due to their wide biotechnological applications. The effectiveness of …
Molecular mechanism of Ras-related protein Rab-5A and effect of mutations in the catalytically active phosphate-binding loop
Ras-related protein (Rab-5a) is primarily involved in the regulation of early endosome fusion
during endocytosis and takes part in the budding process. During GTP hydrolysis, Rab5a …
during endocytosis and takes part in the budding process. During GTP hydrolysis, Rab5a …