Transcriptional regulation by the phosphorylation-dependent factor CREB
B Mayr, M Montminy - Nature reviews Molecular cell biology, 2001 - nature.com
The transcription factor CREB? for'cyclic AMP response element-binding protein'? functions
in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in …
in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in …
Migraine pathophysiology: lessons from mouse models and human genetics
MD Ferrari, RR Klever, GM Terwindt, C Ayata… - The Lancet …, 2015 - thelancet.com
Migraine is a common, disabling, and undertreated episodic brain disorder that is more
common in women than in men. Unbiased genome-wide association studies have identified …
common in women than in men. Unbiased genome-wide association studies have identified …
Genome-wide meta-analysis identifies new susceptibility loci for migraine
Migraine is the most common brain disorder, affecting approximately 14% of the adult
population, but its molecular mechanisms are poorly understood. We report the results of a …
population, but its molecular mechanisms are poorly understood. We report the results of a …
The LIM domain: from the cytoskeleton to the nucleus
JL Kadrmas, MC Beckerle - Nature reviews Molecular cell biology, 2004 - nature.com
First described 15 years ago as a cysteine-rich sequence that was common to a small group
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …
of homeodomain transcription factors, the LIM domain is now recognized as a tandem zinc …
The foot-and-mouth epidemic in Great Britain: pattern of spread and impact of interventions
We present an analysis of the current foot-and-mouth disease epidemic in Great Britain over
the first 2 months of the spread of the virus. The net transmission potential of the pathogen …
the first 2 months of the spread of the virus. The net transmission potential of the pathogen …
What turns CREB on?
M Johannessen, MP Delghandi, U Moens - Cellular signalling, 2004 - Elsevier
The transactivation domain of the cAMP response element-binding protein (CREB) consists
of two major domains. The glutamine-rich Q2 domain, which interacts with the general …
of two major domains. The glutamine-rich Q2 domain, which interacts with the general …
The sarcomeric Z-disc: a nodal point in signalling and disease
D Frank, C Kuhn, HA Katus, N Frey - Journal of molecular medicine, 2006 - Springer
The perception of the Z-disc in striated muscle has undergone significant changes in the
past decade. Traditionally, the Z-disc has been viewed as a passive constituent of the …
past decade. Traditionally, the Z-disc has been viewed as a passive constituent of the …
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2
S Lange, D Auerbach, P McLoughlin… - Journal of cell …, 2002 - journals.biologists.com
During sarcomere contraction skeletal and cardiac muscle cells consume large amounts of
energy. To satisfy this demand, metabolic enzymes are associated with distinct regions of …
energy. To satisfy this demand, metabolic enzymes are associated with distinct regions of …
[PDF][PDF] Early growth response 1—a transcription factor in the crossfire of signal transduction cascades
JI Pagel, E Deindl - 2011 - academia.edu
Early growth response-1 (Egr-1) is a Cys2-His2-type zinc-finger transcription factor. A broad
range of extracellular stimuli is capable of activating Egr-1, thus mediating growth …
range of extracellular stimuli is capable of activating Egr-1, thus mediating growth …
Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes
L Soreq, N Salomonis, M Bronstein… - Frontiers in molecular …, 2013 - frontiersin.org
MicroRNAs (miRNAs) are key post transcriptional regulators of their multiple target genes.
However, the detailed profile of miRNA expression in Parkinson's disease, the second most …
However, the detailed profile of miRNA expression in Parkinson's disease, the second most …