Obesity has become a major epidemic in the 21st century. It increases the risk of
dyslipidemia, hypertension, and type 2 diabetes, which are known cardiometabolic risk …

With the exception of a few monogenic forms, Alzheimer disease (AD) has a complex
aetiology that is likely to involve multiple susceptibility genes and environmental factors. The …

Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

Males and females differ in their immunological responses to foreign and self-antigens and
show distinctions in innate and adaptive immune responses. Certain immunological sex …

Obesity is among the most common and costly chronic disorders worldwide. Estimates
suggest that in the United States obesity affects one-third of adults, accounts for up to one …

The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Though clinical trials for medical applications of dimethyl sulfoxide (DMSO) reported toxicity
in the 1960s, later, the FDA classified DMSO in the safest solvent category. DMSO became …

Major differences between men and women exist in epidemiology, manifestation,
pathophysiology, treatment, and outcome of cardiovascular diseases (CVD), such as …

Malnutrition, which encompasses under-and overnutrition, is responsible for an enormous
morbidity and mortality burden globally. Malnutrition results from disordered nutrient …

Both sex (ie, biological differences) and gender (ie, social or cultural influences) impact
vaccine acceptance, responses, and outcomes. Clinical data illustrate that among children …