The evolving landscape of salivary gland tumors

CE Steuer, GJ Hanna, K Viswanathan… - CA: a cancer journal …, 2023 - Wiley Online Library
Salivary gland cancers are a rare, histologically diverse group of tumors. They range from
indolent to aggressive and can cause significant morbidity and mortality. Surgical resection …

Adenoid cystic carcinoma of the head and neck–An update

A Coca-Pelaz, JP Rodrigo, PJ Bradley… - Oral oncology, 2015 - Elsevier
This article provides an update on the current understanding of adenoid cystic carcinoma of
the head and neck, including a review of its epidemiology, clinical behavior, pathology …

Management of salivary gland malignancy: ASCO guideline

JL Geiger, N Ismaila, B Beadle, JJ Caudell… - Journal of Clinical …, 2021 - ascopubs.org
PURPOSE To provide evidence-based recommendations for practicing physicians and
other healthcare providers on the management of salivary gland malignancy. METHODS …

Targeting the EGFR signaling pathway in cancer therapy

P Seshacharyulu, MP Ponnusamy… - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Cancer is a devastating disease; however, several therapeutic advances have
recently been made, wherein EGFR and its family members have emerged as useful …

The mutational landscape of adenoid cystic carcinoma

AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly… - Nature …, 2013 - nature.com
Adenoid cystic carcinomas (ACCs) are among the most enigmatic of human malignancies.
These aggressive salivary gland cancers frequently recur and metastasize despite definitive …

Targeting the disordered C terminus of PTP1B with an allosteric inhibitor

N Krishnan, D Koveal, DH Miller, B Xue… - Nature chemical …, 2014 - nature.com
PTP1B, a validated therapeutic target for diabetes and obesity, has a critical positive role in
HER2 signaling in breast tumorigenesis. Efforts to develop therapeutic inhibitors of PTP1B …

Major and minor salivary gland tumors

M Guzzo, LD Locati, FJ Prott, G Gatta, M McGurk… - Critical reviews in …, 2010 - Elsevier
Malignant salivary gland tumors are rare. The most common tumor site is the parotid.
Aetiologic factors are not clear. Nutrition may be a risk factor, as well as irradiation or a long …

Adenoid cystic carcinoma: a review of recent advances, molecular targets, and clinical trials

PM Dillon, S Chakraborty, CA Moskaluk, PJ Joshi… - Head & …, 2016 - Wiley Online Library
Background Adenoid cystic carcinoma (ACC) is a rare tumor of secretory glands. In this
study, recent advances in molecular characterization and in therapeutics are reviewed …

[HTML][HTML] Systemic therapies for salivary gland adenoid cystic carcinoma

S Sahara, AE Herzog, JE Nör - American Journal of Cancer …, 2021 - ncbi.nlm.nih.gov
Adenoid cystic carcinoma (ACC) is a slow growing, but relentless cancer. Due to its rarity
and lack of understanding of its molecular etiology, no standard chemotherapy for ACC …

Systemic therapy in the management of metastatic or locally recurrent adenoid cystic carcinoma of the salivary glands: a systematic review

SA Laurie, AL Ho, MG Fury, E Sherman… - The lancet …, 2011 - thelancet.com
Adenoid cystic carcinomas (ACC) are rare cancers usually arising in the salivary glands.
Once metastatic, the natural history can vary; some patients with indolent cancer remain …