Owing to their significant physiological functions, especially as selective relays for
translocation of physiological relevant species through cellular membranes, natural ion …

Gramicidin S, natural antimicrobial peptide is used commercially in medicinal lozenges for
sore throat and Gram-negative and Gram-positive bacterial infections. However, its clinical …

We report herein the first systematic crystal structural investigation of azaproline
incorporated in homo‐and heterochiral diprolyl peptides. The X‐ray crystallography data of …

The rise of antibiotic resistance has necessitated the development of alternative strategies
for the treatment of infectious diseases. Antimicrobial peptides (AMPs), components of the …

Aufgrund ihrer wichtigen physiologischen Funktionen, insbesondere als selektive Relais für
die Translokation physiologisch relevanter Spezies durch Zellmembranen, spielen …

Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant
Staphylococcus aureus (VRSA) are primary causes of skin and soft tissue infections …

Infections caused by drug-resistant pathogens are a worldwide challenge for public health.
Antimicrobial peptides (AMPs) are regarded as promising antibiotic alternatives for the …

Summary of main observation and conclusion Gramicidin A is a natural peptide, which
shows high antimicrobial activity to Gram‐positive bacteria. However, the hemolytic toxicity …

The hydrogen bonding interaction between an amide N− H and the amide N of the
preceding residue is prevalent in proline‐containing proteins and peptides. However, the N …

The effects of replacement with aza groups in the proline ring on the conformational
preference and prolyl cis–trans isomerization were investigated for Ac-X-OMe (X= α-azPro, β …