The COVID-19 vaccine race: challenges and opportunities in vaccine formulation
In the race for a safe and effective vaccine against coronavirus disease (COVID)-19,
pharmaceutical formulation science plays a critical role throughout the development …
pharmaceutical formulation science plays a critical role throughout the development …
Virus-like particles: Revolutionary platforms for developing vaccines against emerging infectious diseases
Virus-like particles (VLPs) are nanostructures that possess diverse applications in
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
therapeutics, immunization, and diagnostics. With the recent advancements in biomedical …
Scaled preparation of extracellular vesicles from conditioned media
S Staubach, FN Bauer, T Tertel, V Börger… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) especially of mesenchymal stem/stomal cells (MSCs) are
increasingly considered as biotherapeutic agents for a variety of different diseases. For …
increasingly considered as biotherapeutic agents for a variety of different diseases. For …
Technological advances towards extracellular vesicles mass production
A Grangier, J Branchu, J Volatron, M Piffoux… - Advanced Drug Delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are becoming essential actors in bio-therapeutics, as much for
their regenerative or immunomodulatory properties as for their potential as cargo delivery …
their regenerative or immunomodulatory properties as for their potential as cargo delivery …
Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications of Sleeping Beauty, piggyBac and Tol2 for Genome Engineering
N Sandoval-Villegas, W Nurieva, M Amberger… - International journal of …, 2021 - mdpi.com
Transposons are mobile genetic elements evolved to execute highly efficient integration of
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
their genes into the genomes of their host cells. These natural DNA transfer vehicles have …
[HTML][HTML] Gene therapy for retinal degenerative diseases: progress, challenges, and future directions
S Drag, F Dotiwala… - … Ophthalmology & Visual …, 2023 - tvst.arvojournals.org
Since long before the first approval of gene therapy for retinal disease, ocular gene therapy
has captured the hopes of patients, clinicians, and scientists alike. Indeed, the retina …
has captured the hopes of patients, clinicians, and scientists alike. Indeed, the retina …
Virus‐like particles as powerful vaccination strategy against human viruses
I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …
also as valuable research materials for various biomedical purposes, including recombinant …
Critical challenges and advances in recombinant adeno‐associated virus (rAAV) biomanufacturing
Gene therapy is a promising therapeutic approach for genetic and acquired diseases
nowadays. Among DNA delivery vectors, recombinant adeno‐associated virus (rAAV) is one …
nowadays. Among DNA delivery vectors, recombinant adeno‐associated virus (rAAV) is one …
Advances in lentivirus purification
AS Moreira, DG Cavaco, TQ Faria… - Biotechnology …, 2021 - Wiley Online Library
Lentiviral vectors (LVs) have been increasingly used as a tool for gene and cell therapies
since they can stably integrate the genome in dividing and nondividing cells. LV production …
since they can stably integrate the genome in dividing and nondividing cells. LV production …
Isolation of extracellular vesicles from microalgae: a renewable and scalable bioprocess
Extracellular vesicles (EVs) play a crucial role as potent signal transducers among cells, with
the potential to operate cross-species and cross-kingdom communication. Nanoalgosomes …
the potential to operate cross-species and cross-kingdom communication. Nanoalgosomes …