Tumor immune microenvironment (TIME) include tumor cells, immune cells, cytokines, etc.
The interactions between these components, which are divided into anti-tumor and pro …

Different stimuli can polarize macrophages into two basic types, M1 and M2. Tumor-
associated macrophages (TAMs) in the tumor microenvironment (TME) are composed of …

The polarization of tumor-associated macrophages (TAMs) from M2 to M1 phenotype
demonstrates great potential for remodeling the immunosuppressive tumor …

The immunosuppressive status of the tumor microenvironment (TME) remains poorly
defined due to a lack of understanding regarding the function of tumor-associated …

Immunotherapy that harnesses the human immune system to fight cancer has received
widespread attention and become a mainstream strategy for cancer treatment. Cancer …

Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Reprogramming the immunosuppressive tumor microenvironment by modulating
macrophages holds great promise in tumor immunotherapy. As a class of professional …

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. PDAC is only
cured by surgical resection in its early stage, but there remains a relatively high possibility of …

Immunotherapy is recognized as one of the most promising approaches to treat cancers.
However, its effect in glioblastoma (GBM) treatment is insufficient, which can in part be …

Cancer remains the leading cause of death worldwide despite advances in treatment
options for patients. As such, safe and effective therapeutics are required. Short peptides …