The endocannabinoid system: a potential target for the treatment of various diseases
H Lowe, N Toyang, B Steele, J Bryant… - International journal of …, 2021 - mdpi.com
The Endocannabinoid System (ECS) is primarily responsible for maintaining homeostasis, a
balance in internal environment (temperature, mood, and immune system) and energy input …
balance in internal environment (temperature, mood, and immune system) and energy input …
Bioactive lipids, inflammation and chronic diseases
A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …
cellular and molecular processes involved in health and disease, of which inflammation …
Endocannabinoid signaling at the periphery: 50 years after THC
In 1964, the psychoactive ingredient of Cannabis sativa, Δ 9-tetrahydrocannabinol (THC),
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …
was isolated. Nearly 30 years later the endogenous counterparts of THC, collectively termed …
Endocannabinoids—at the crossroads between the gut microbiota and host metabolism
Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …
latest advances in the metabolism field, the discovery that gut microorganisms have a major …
Cannabinoids and cytochrome P450 interactions
O Zendulka, G Dovrtelova, K Nosková… - Current drug …, 2016 - ingentaconnect.com
Objective: This review consists of three parts, representing three different possibilities of
interactions between cannabinoid receptor ligands of both exogenous and endogenous …
interactions between cannabinoid receptor ligands of both exogenous and endogenous …
Developmental origins of NAFLD: a womb with a clue
SR Wesolowski, KCE Kasmi, KR Jonscher… - Nature reviews …, 2017 - nature.com
Abstract Changes in the maternal environment leading to an altered intrauterine milieu can
result in subtle insults to the fetus, promoting increased lifetime disease risk and/or disease …
result in subtle insults to the fetus, promoting increased lifetime disease risk and/or disease …
Endocannabinoid system components as potential biomarkers in psychiatry
F Navarrete, MS García-Gutiérrez… - Frontiers in …, 2020 - frontiersin.org
The high heterogeneity of psychiatric disorders leads to a lack of diagnostic precision.
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …
Therefore, the search of biomarkers is a fundamental aspect in psychiatry to reach a more …
Metabolism of the endocannabinoid anandamide: open questions after 25 years
M Maccarrone - Frontiers in molecular neuroscience, 2017 - frontiersin.org
Cannabis extracts have been used for centuries, but its main active principle∆ 9-
tetrahydrocannabinol (THC) was identified about 50 years ago. Yet, it is only 25 years ago …
tetrahydrocannabinol (THC) was identified about 50 years ago. Yet, it is only 25 years ago …
A guide to targeting the endocannabinoid system in drug design
A Stasiulewicz, K Znajdek, M Grudzień… - International journal of …, 2020 - mdpi.com
The endocannabinoid system (ECS) is one of the most crucial systems in the human
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
organism, exhibiting multi-purpose regulatory character. It is engaged in a vast array of …
The role of the endocannabinoid system in female reproductive tissues
OLS Walker, AC Holloway, S Raha - Journal of ovarian research, 2019 - Springer
There has been increasing interest in the role of endocannabinoids as critical modulators of
the female reproductive processes. Endocannabinoids are natural ligands of cannabinoid …
the female reproductive processes. Endocannabinoids are natural ligands of cannabinoid …