DNA methylation is the most well studied of the epigenetic regulators in relation to
environmental exposures. To date, numerous studies have detailed the manner by which …

Toxic heavy metals (THMs) are non-essential hazardous environmental pollutants with
intractable health challenges in humans and animals. Exposure to lead (Pb), cadmium (Cd) …

Current evidence supports the notion that environmental exposures are associated with
DNA-methylation and expression changes that can impact human health. Our objective was …

Dietary cadmium exposure was recently found to alter DNA methylation in adults, but data
on effects early in life are lacking. Our objective was to evaluate associations between …

Transposable elements (TEs) comprise a group of repetitive sequences that bring positive,
negative, as well as neutral effects to the host organism. Earlier considered as “junk DNA,” …

Genetic studies traditionally focus on DNA as the molecule that passes information on from
parents to their offspring. Changes in the DNA code alter heritable information and can more …

Background: The epigenetic effects of individual environmental toxicants in tobacco remain
largely unexplored. Cadmium (Cd) has been associated with smoking-related health effects …

Early-life inorganic arsenic exposure influences not only child health and development but
also health in later life. The adverse effects of arsenic may be mediated by epigenetic …

Exposure to environmental contaminants during pregnancy has been linked to adverse
outcomes at birth and later in life. The link between prenatal exposures and latent health …

It is thought that germ cells and preimplantation embryos during development are most
susceptible to endogenous and exogenous environmental factors because the epigenome …