The T cell receptor (TCR) complex is a naturally occurring antigen sensor that detects,
amplifies and coordinates cellular immune responses to epitopes derived from cell surface …

T cells in the immune system protect the human body from infection by pathogens and clear
mutant cells through specific recognition by T cell receptors (TCRs). Cancer immunotherapy …

T cell discrimination of self and non-self is predicated on αβ T cell receptor (TCR) co-
recognition of peptides presented by MHC molecules. Over the past 20 years, structurally …

T cell receptors (TCRs) are protein complexes formed by six different polypeptides. In most T
cells, TCRs are composed of αβ subunits displaying immunoglobulin-like variable domains …

Sazacytidine treatment of mouse C3HlOT1/2 embryonic fibroblasts converts them to
myoblasts at a frequency suggesting alteration of one or only a few closely linked regulatory …

This year marks the 25th anniversary of the first Annual Review of Immunology article to
describe features of the T cell antigen receptor (TCR). In celebration of this anniversary, we …

The four distinct T-cell antigen receptor polypeptides (α, β, γ, δ) form two different
heterodimers (α: β and γ: δ) that are very similar to immunoglobulins in primary sequence …

We present a new approach to the study of the immune system that combines techniques of
systems biology with information provided by data-driven prediction methods. To this end …

The characteristics of an organism are determined by the genes expressed within it. A
method was developed, called serial analysis of gene expression (SAGE), that allows the …

This standard-setting textbook has defined the field of immunology since 1984, and is now in
its Seventh Edition continuing to deliver the detailed, authoritative, and timely coverage …