Bioresponsive materials

Y Lu, AA Aimetti, R Langer, Z Gu - Nature Reviews Materials, 2016 - nature.com
Abstract 'Smart'bioresponsive materials that are sensitive to biological signals or to
pathological abnormalities, and interact with or are actuated by them, are appealing …

Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior

YS Chatzizisis, AU Coskun, M Jonas… - Journal of the American …, 2007 - jacc.org
Although the entire coronary tree is exposed to the atherogenic effect of the systemic risk
factors, atherosclerotic lesions form at specific arterial regions, where low and oscillatory …

Transformable liquid-metal nanomedicine

Y Lu, Q Hu, Y Lin, DB Pacardo, C Wang, W Sun… - Nature …, 2015 - nature.com
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …

Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance

B Rode, J Shi, N Endesh, MJ Drinkhill… - Nature …, 2017 - nature.com
Mammalian biology adapts to physical activity but the molecular mechanisms sensing the
activity remain enigmatic. Recent studies have revealed how Piezo1 protein senses …

Endothelial shear stress in the evolution of coronary atherosclerotic plaque and vascular remodelling: current understanding and remaining questions

JJ Wentzel, YS Chatzizisis, FJH Gijsen… - Cardiovascular …, 2012 - academic.oup.com
The heterogeneity of plaque formation, the vascular remodelling response to plaque
formation, and the consequent phenotype of plaque instability attest to the extraordinarily …

Role of hemodynamic shear stress in cardiovascular disease

E Cecchi, C Giglioli, S Valente, C Lazzeri, GF Gensini… - Atherosclerosis, 2011 - Elsevier
Atherosclerosis is the main cause of morbidity and mortality in the Western world.
Inflammation and blood flow alterations are new markers emerging as possible …

[图书][B] Snapshots of hemodynamics: an aid for clinical research and graduate education

N Westerhof, N Stergiopulos, MIM Noble, BE Westerhof - 2018 - books.google.com
This book is written in a quick reference style to help clinical and basic researchers, as well
as graduate students, in the understanding of hemodynamics. Recent dev-opments in …

Image-based modeling of blood flow and vessel wall dynamics: applications, methods and future directions: Sixth International Bio-Fluid Mechanics Symposium and …

CA Taylor, DA Steinman - Annals of biomedical engineering, 2010 - Springer
The objective of our session at the 2008 International Bio-Fluid Symposium and Workshop
was to review the state-of-the-art in image-based modeling of blood flow, and identify future …

Shear-stress sensitive lenticular vesicles for targeted drug delivery

MN Holme, IA Fedotenko, D Abegg, J Althaus… - Nature …, 2012 - nature.com
Atherosclerosis results in the narrowing of arterial blood vessels and this causes significant
changes in the endogenous shear stress between healthy and constricted arteries …

The critical role of hemodynamics in the development of cerebral vascular disease: a review

AM Nixon, M Gunel, BE Sumpio - Journal of neurosurgery, 2010 - thejns.org
Atherosclerosis and intracranial saccular aneurysms predictably localize in areas with
complex arterial geometries such as bifurcations and curvatures. These sites are …