Engineering precise sequence-defined polymers for advanced functions
Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …
Unnatural helical peptidic foldamers as protein segment mimics
P Sang, J Cai - Chemical Society Reviews, 2023 - pubs.rsc.org
Unnatural helical peptidic foldamers have attracted considerable attention owing to their
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
unique folding behaviours, diverse artificial protein binding mechanisms, and promising …
Advances in development of antimicrobial peptidomimetics as potential drugs
The rapid emergence of multidrug-resistant pathogens has evolved into a global health
problem as current treatment options are failing for infections caused by pan-resistant …
problem as current treatment options are failing for infections caused by pan-resistant …
Sequence-defined synthetic polymers for new-generation functional biomaterials
Synthetic polymers have been extensively exploited for biomedical and pharmacological
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …
applications, spanning from surgical devices, diagnostics, tissue engineering, regenerative …
Novel antimicrobial peptides modified with fluorinated sulfono-γ-AA having high stability and targeting multidrug-resistant bacteria infections
X Guo, X Miao, Y An, T Yan, Y Jia, B Deng, J Cai… - European Journal of …, 2024 - Elsevier
The emergence and increasing prevalence of multidrug-resistant (MDR) bacteria have
posed an urgent demand for novel antibacterial drugs. Currently, antimicrobial peptides …
posed an urgent demand for novel antibacterial drugs. Currently, antimicrobial peptides …
Natural antifungal peptides/proteins as model for novel food preservatives
T Thery, KM Lynch, EK Arendt - … in food science and food safety, 2019 - Wiley Online Library
A large range of ingredients for food and food products are subject to fungal contamination,
which is a major cause of destruction of crops, exposure of animals and humans to invasive …
which is a major cause of destruction of crops, exposure of animals and humans to invasive …
Polycarbonates with potent and selective antimicrobial activity toward gram-positive bacteria
A Nimmagadda, X Liu, P Teng, M Su, Y Li… - …, 2017 - ACS Publications
The resistance developed by life-threatening bacteria toward conventional antibiotics has
become a major concern in public health. To combat antibiotic resistance, there has been a …
become a major concern in public health. To combat antibiotic resistance, there has been a …
Amino sulfonic acids, peptidosulfonamides and other related compounds
OO Grygorenko, AV Biitseva, S Zhersh - Tetrahedron, 2018 - Elsevier
A review with 636 references. The literature on saturated amino sulfonic acids with
primary/secondary amino group and their derivatives from XIX century to 2016 is surveyed …
primary/secondary amino group and their derivatives from XIX century to 2016 is surveyed …
Sequence-defined backbone modifications regulate antibacterial activity of oligoTEAs
In response to the urgent need for new antibiotic development strategies, antimicrobial
peptides (AMPs) and other synthetic polymers are being actively investigated as promising …
peptides (AMPs) and other synthetic polymers are being actively investigated as promising …
Rational Design of Dimeric Lysine N-Alkylamides as Potent and Broad-Spectrum Antibacterial Agents
Y Niu, M Wang, Y Cao, A Nimmagadda… - Journal of Medicinal …, 2018 - ACS Publications
Antibiotic resistance is one of the biggest threats to public health, and new antibacterial
agents hence are in an urgent need to combat infectious diseases caused by multidrug …
agents hence are in an urgent need to combat infectious diseases caused by multidrug …