Although cyclodextrins (CDs) have been studied for over 100 years and can be found in at
least 35 pharmaceutical products, they are still regarded as novel pharmaceutical …

Cyclodextrins (CDs) are naturally available water-soluble cyclic oligosaccharides widely
used as carriers in the pharmaceutical industry for their ability to modulate several properties …

Cyclodextrins (CDs) are macrocyclic oligosaccharides composed of α (1, 4)-linked
glucopyranose subunits. These molecules possess a cage-like supramolecular structure …

In this paper we investigated the inclusion complexation between zerumbone (ZER) and
hydroxylpropyl-β-cyclodextrin (HPβCD) at four different temperatures: 293–318° K. The …

Abstract The curcumin (CUR)-hydroxypropyl-β-cyclodextrin (HP-β-CD) inclusion complex
(CUR-HP-β-CD) was prepared to erase its therapeutic restrictions of poor aqueous solubility …

Objective: Intraocular pressure has always been a great challenge for topical ophthalmic
drugs. The study aimed to develop ocular surfactant based nanovesicles (NVs) carried in …

About 40% of newly-discovered entities are poorly soluble in water, and this may be an
obstacle in the creation of new drugs. To address this problem, the present review article …

The aqueous solubility of active drug moiety plays a crucial role in the development of an
efficacious formulation. The poor aqueous solubility of BCS class II and IV drugs is …

Carbonic anhydrase inhibitors (CAIs) are used as systemic and topical agents for lowering
intraocular pressure (IOP) in patients with glaucoma. Owing to the wide distribution of CAs …

Inclusion complex of trazodone hydrochloride (TRD) with hydroxypropyl-β-cyclodextrin (HP-
βCD) has been investigated by 1H NMR, 13CNMR, 2D NMR, FTIR and UV/visible …