Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are characterized by deposits of amyloid proteins. The homeostasis of metal ions is …

The polyhistidine (6XHis) motif is one of the most ubiquitous protein purification tags. The
6XHis motif enables the binding of tagged proteins to various metals, which can be …

The involvement of metal ions in interactions with therapeutic peptides is inevitable. They
are one of the factors able to fine-tune the biological properties of antimicrobial peptides, a …

Can a minor difference in the nonmetal binding sequence of antimicrobial clavanins explain
the drastic change in the coordination environment and antimicrobial efficiency? This study …

Snake venoms are complex mixtures of toxic and often spectacularly biologically active
components. Some African vipers contain polyhistidine and polyglycine peptides, which play …

Protein-protein interactions play important roles for a variety of cell functions, often involving
metal ions; in fact, metal-ion binding mediates and regulates the activity of a wide range of …

Membrane environment often has an important effect on the structure, and therefore also on
the coordination mode of biologically relevant metal ions. This is also true in the case of Cu …

It is supposed that the presence of poly-His regions in close proximity to poly-Gly domains in
snake venoms is related to their biological activity; poly-His/poly-Gly (pHpG) peptides inhibit …

Calcitermin, an antimicrobial peptide from the fluid of the human airways, is a well-
conserved, 15 amino acid C-terminal cleavage fragment of calgranulin C …

The antimicrobial activity of surfactant-associated anionic peptides (SAAPs), which are
isolated from the ovine pulmonary surfactant and are selective against the ovine pathogen …