AlphaFold2 (AF) is a promising tool, but is it accurate enough to predict single mutation
effects? Here, we report that the localized structural deformation between protein pairs …

Diffraction-based structural methods contribute a large fraction of the biomolecular structural
models available, providing a critical understanding of macromolecular architecture. These …

The web-based IceBear software is a versatile tool to monitor the results of crystallization
experiments and is designed to facilitate supervisor and student communications. It also …

Structural analysis of proteins using X-ray crystallography is crucial for discovering their
biochemical functionalities. However, growing X-ray-quality crystals of proteins is often a …

AlphaFold2 (AF) is a promising tool, but is it accurate enough to predict single mutation
effects? Here, we report that the localized structural deformation between protein pairs …

X-ray crystallography is the most commonly employed technique to discern macromolecular
structures, but the crucial step of crystallizing a protein into an ordered lattice amenable to …

AlphaFold2 (AF2) is a promising tool for structural biology, but is it sufficiently accurate to
predict the effect of missense mutations? We find that structural variation between closely …

Polo is a Python‐based graphical user interface designed to streamline viewing and
analysis of images to monitor crystal growth, with a specific target to enable users of the …

Biological data sources are important in several scientific fields, such as bioinformatics,
systems biology, and genomics. Biological sources have played an essential role in …

Protein crystallization has for decades been a critical and restrictive step in macromolecular
structure determination via X-ray diffraction. Crystallization typically involves a multi-stage …