The burgeoning field of leukocyte trafficking has created new and exciting opportunities in
the clinic. Trafficking signals are being defined that finely control the movement of distinct …

Lymphocytes are imprinted during activation with trafficking programs (combinations of
adhesion and chemoattractant receptors) that target their migration to specific tissues and …

Nonalcoholic fatty liver disease (NAFLD) encompasses a range of manifestations, including
steatosis and cirrhosis. Progressive disease is characterized by hepatic leukocyte …

Although the adhesive interactions of leukocytes with endothelial cells are well understood,
little is known about the detailed mechanisms underlying the actual migration of leukocytes …

A hallmark feature of inflammation is the orchestrated recruitment of neutrophils from the
bloodstream into inflamed tissue. Although selectins and integrins mediate recruitment in …

Leukocyte trafficking between the blood and the tissues is pivotal for normal immune
responses. Cell-adhesion molecules (such as selectins and leukocyte integrins) and …

Abstract Significance: Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that oxidates
primary amines in a reaction producing also hydrogen peroxide. VAP-1 on the blood vessel …

Pericryptal myofibroblasts in the colon and rectum play an important role in regulating the
normal colorectal stem cell niche and facilitating tumor progression. Myofibroblasts …

Abstract Vascular adhesion protein-1 (VAP-1) is a member of the copper-containing amine
oxidase/semicarbazide-sensitive amine oxidase (AOC/SSAO) enzyme family. SSAO …

Leukocyte migration to sites of inflammation is regulated by several endothelial adhesion
molecules. Vascular adhesion protein-1 (VAP-1) is unique among the homing-associated …