Mast cells are important components of the immune system, and they perform pro-
inflammatory as well as anti-inflammatory roles in the complex process of immune regulation …

Mast cells are versatile effector cells of the immune system, contributing to both innate and
adaptive immunity toward pathogens but also having profound detrimental activities in the …

Exosomes are vesicles of endocytic origin released by many cells. These vesicles can
mediate communication between cells, facilitating processes such as antigen presentation …

Two novel stem cell factor (SCF) dependent human mast cell lines, designated LAD 1 and 2,
were established from bone marrow aspirates from a patient with mast cell …

The factors that control migration of mast cells to sites of inflammation and tissue repair
remain largely undefined. Whereas several recent studies have described chemotactic …

Mast cells have been implicated in various diseases that are accompanied by
neovascularization. The exact mechanisms by which mast cells might mediate an …

Background Mast cells, the key cells of immediate hypersensitivity type reactions, have also
been postulated to have a central role in influencing tissue remodelling and fibrosis …

Adenosine potentiates mast cell activation, but the receptor type and molecular mechanisms
involved have not been defined. We, therefore, investigated the effects of adenosine on the …

Mast cells, essential effector cells in allergic inflammation, have been found to be activated
in T cell-mediated inflammatory processes in accordance with their residence in close …

The mast cell is one of the major effector cells in inflammatory reactions and can be found in
most tissues throughout the body. During inflammation, an increase in the number of mast …