[HTML][HTML] Antimicrobial peptides: A new hope in biomedical and pharmaceutical fields

A Moretta, C Scieuzo, AM Petrone, R Salvia… - Frontiers in cellular …, 2021 - frontiersin.org
Antibiotics are essential drugs used to treat pathogenic bacteria, but their prolonged use
contributes to the development and spread of drug-resistant microorganisms. Antibiotic …

Antimicrobial peptides as therapeutic agents: Opportunities and challenges

M Mahlapuu, C Björn, J Ekblom - Critical reviews in biotechnology, 2020 - Taylor & Francis
The rapid development of microbial resistance to conventional antibiotics has accelerated
efforts to find anti-infectives with a novel mode-of-action, which are less prone to bacterial …

Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability

Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Cubosomes: the next generation of smart lipid nanoparticles?

HMG Barriga, MN Holme… - Angewandte Chemie …, 2019 - Wiley Online Library
Cubosomes are highly stable nanoparticles formed from the lipid cubic phase and stabilized
by a polymer based outer corona. Bicontinuous lipid cubic phases consist of a single lipid …

Bioavailability of nutraceuticals: Role of the food matrix, processing conditions, the gastrointestinal tract, and nanodelivery systems

C Dima, E Assadpour, S Dima… - … reviews in food science …, 2020 - Wiley Online Library
Nowadays, many consumers prefer foods with a high content of nutraceuticals that
contribute to the prevention or healing of chronic diseases. Therefore, in recent years, more …

Cubosomes as an emerging platform for drug delivery: A review of the state of the art

MAS Abourehab, MJ Ansari, A Singh… - Journal of Materials …, 2022 - pubs.rsc.org
Lipid-based drug-delivery nanoparticles, including non-lamellar-type, mesophasic
nanostructured materials of lyotropic liquid crystals (LLCs), have been a topic of interest for …

[HTML][HTML] Antimicrobial peptides–unleashing their therapeutic potential using nanotechnology

S Gera, E Kankuri, K Kogermann - Pharmacology & Therapeutics, 2022 - Elsevier
Antimicrobial peptides (AMPs) are potent, mostly cationic, and amphiphilic broad-spectrum
host defense antimicrobials that are produced by all organisms ranging from prokaryotes to …

In pursuit of next-generation therapeutics: Antimicrobial peptides against superbugs, their sources, mechanism of action, nanotechnology-based delivery, and clinical …

A Thakur, A Sharma, HK Alajangi, PK Jaiswal… - International Journal of …, 2022 - Elsevier
Antimicrobial peptides (AMPs) attracted attention as potential source of novel antimicrobials.
Multi-drug resistant (MDR) infections have emerged as a global threat to public health in …

Cubosomes for topical delivery of the antimicrobial peptide LL-37

L Boge, K Hallstensson, L Ringstad… - European journal of …, 2019 - Elsevier
In this study, the use of cubosomes for topical delivery of the antimicrobial peptide (AMP) LL-
37 was investigated. Topical delivery of AMPs is of great interest for treatment of skin …