Transcription: insights from the HIV-1 promoter

E Ne, RJ Palstra, T Mahmoudi - International review of cell and molecular …, 2018 - Elsevier
In this review, we cover transcription regulation of human immunodeficiency virus type 1
(HIV-1) gene expression, focusing on the invaluable contributions, made by HIV research …

HIV-1 coreceptor usage, transmission, and disease progression

SM Philpott - Current HIV research, 2003 - ingentaconnect.com
HIV-1 coreceptor usage is believed to play a critical role in pathogenesis. To initiate
infection, HIV-1 interacts with two cell surface receptors, CD4 is the primary receptor and the …

The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C

T Cilliers, J Nhlapo, M Coetzer, D Orlovic… - Journal of …, 2003 - Am Soc Microbiol
Human immunodeficiency virus type 1 (HIV-1) subtype C viruses with different coreceptor
usage profiles were isolated from 29 South African patients with advanced AIDS. All 24 R5 …

Multiple NF-κB sites in HIV-1 subtype C long terminal repeat confer superior magnitude of transcription and thereby the enhanced viral predominance

M Bachu, S Yalla, M Asokan, A Verma, U Neogi… - Journal of Biological …, 2012 - ASBMB
We demonstrate that at least three different promoter variant strains of HIV-1 subtype C have
been gradually expanding and replacing the standard subtype C viruses in India, and …

Evolution and diversity of HIV-1 in Africa–a review

MA Papathanasopoulos, GM Hunt, CT Tiemessen - Virus genes, 2003 - Springer
The HIV/AIDS pandemic represents a major development crisis for the African continent,
which is the worst affected region in the world. Currently, almost 30 of the 42 million people …

Laboratory evaluation of the Liat HIV Quant (IQuum) whole-blood and plasma HIV-1 viral load assays for point-of-care testing in South Africa

L Scott, N Gous, S Carmona… - Journal of clinical …, 2015 - Am Soc Microbiol
ABSTRACT Point-of-care (POC) HIV viral load (VL) testing offers the potential to reduce
turnaround times for antiretroviral therapy monitoring, offer near-patient acute HIV diagnosis …

Prediction of HIV type 1 subtype C tropism by genotypic algorithms built from subtype B viruses

S Raymond, P Delobel, M Mavigner… - JAIDS Journal of …, 2010 - journals.lww.com
Background: Genotypic predictions of HIV-1 tropism could simplify CCR5 antagonist usage.
However, the genotypic algorithms built from subtype B viruses could be inadequate for non …

[HTML][HTML] Use of alternate coreceptors on primary cells by two HIV-1 isolates

T Cilliers, S Willey, WM Sullivan, T Patience, P Pugach… - Virology, 2005 - Elsevier
Two HIV-1 isolates (CM4 and CM9) able to use alternate HIV-1 coreceptors on transfected
cell lines were tested for their sensitivity to inhibitors of HIV-1 entry on primary cells. CM4 …

[HTML][HTML] HIV-1 subtype C in vitro growth and coreceptor utilization

T Ndung'u, E Sepako, MF McLane, F Chand, K Bedi… - Virology, 2006 - Elsevier
Human immunodeficiency virus type 1 subtype C (HIV-1C) accounts for about 50% of all HIV
infections in the pandemic and is the predominant subtype in the heavily burdened region of …

HIV population genotypic tropism testing and its clinical significance

M Obermeier, J Symons… - Current Opinion in HIV …, 2012 - journals.lww.com
HIV population genotypic tropism testing and its clinical si... : Current Opinion in HIV and AIDS
HIV population genotypic tropism testing and its clinical significance : Current Opinion in HIV …