[HTML][HTML] Defining the role of the tumor vasculature in antitumor immunity and immunotherapy
MB Schaaf, AD Garg, P Agostinis - Cell death & disease, 2018 - nature.com
It is now well established that cancer cells co-exist within a complex environment with
stromal cells and depend for their growth and dissemination on tight and plastic interactions …
stromal cells and depend for their growth and dissemination on tight and plastic interactions …
[HTML][HTML] Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy
Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or
cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal …
cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal …
Immune checkpoint inhibitors in advanced non–small cell lung cancer
HI Assi, AO Kamphorst, NM Moukalled… - Cancer, 2018 - Wiley Online Library
The emergence of immune checkpoint inhibitors for the treatment of cancer has led to major
changes to the therapeutic landscape of lung cancer. Improvements in overall survival …
changes to the therapeutic landscape of lung cancer. Improvements in overall survival …
Theranostics using antibodies and antibody-related therapeutics
KL Moek, D Giesen, IC Kok, DJA de Groot… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In theranostics, radiolabeled compounds are used to determine a treatment strategy by
combining therapeutics and diagnostics in the same agent. Monoclonal antibodies (mAbs) …
combining therapeutics and diagnostics in the same agent. Monoclonal antibodies (mAbs) …
[HTML][HTML] Comprehensive analysis of the tumor immune micro-environment in non-small cell lung cancer for efficacy of checkpoint inhibitor
Characterizing the molecular immune subtype and micro-environment of lung cancer is
necessary to understand immunogenic interactions between infiltrating immune and stromal …
necessary to understand immunogenic interactions between infiltrating immune and stromal …
Predictors for clinical benefit of immune checkpoint inhibitors in advanced non-small-cell lung cancer: a meta-analysis
H El-Osta, S Jafri - Immunotherapy, 2019 - Taylor & Francis
Aim: In this meta-analysis, we evaluated several predictors of benefit to single-agent
immune checkpoint inhibitors (ICIs) in metastatic non-small-cell lung cancer (NSCLC) …
immune checkpoint inhibitors (ICIs) in metastatic non-small-cell lung cancer (NSCLC) …
Predictability of Neutrophile to Lymphocyte Ratio and Platelet to Lymphocyte Ratio on the Effectiveness of Immune Checkpoint Inhibitors in Non-small Cell Lung …
CTT Nguyen, TNK Van, PT Huong - Cancer Control, 2024 - journals.sagepub.com
Objectives The associations between the neutrophil-lymphocyte ratio (NLR) and platelet-to-
lymphocyte ratio (PLR) with the responses of non-small cell lung cancer (NSCLC) patients …
lymphocyte ratio (PLR) with the responses of non-small cell lung cancer (NSCLC) patients …
[HTML][HTML] Biological bases of immune-related adverse events and potential crosslinks with immunogenic effects of radiation
L Bardoscia, N Pasinetti, L Triggiani, S Cozzi… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors have gained an established role in the treatment of different
tumors. Indeed, their use has dramatically changed the landscape of cancer care, especially …
tumors. Indeed, their use has dramatically changed the landscape of cancer care, especially …
[HTML][HTML] Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer
D Dhawan, NM Hahn, JA Ramos-Vara… - PLoS genetics, 2018 - journals.plos.org
There is growing evidence that molecular subtypes (eg luminal and basal subtypes) affect
the prognosis and treatment response in patients with muscle invasive urinary bladder …
the prognosis and treatment response in patients with muscle invasive urinary bladder …
[HTML][HTML] Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance
Recent efforts on genome wide profiling of muscle invasive bladder cancer (MIBC) have led
to its classification into distinct genomic and transcriptomic molecular subtypes that exhibit …
to its classification into distinct genomic and transcriptomic molecular subtypes that exhibit …