[HTML][HTML] Defining the role of the tumor vasculature in antitumor immunity and immunotherapy

MB Schaaf, AD Garg, P Agostinis - Cell death & disease, 2018 - nature.com
It is now well established that cancer cells co-exist within a complex environment with
stromal cells and depend for their growth and dissemination on tight and plastic interactions …

[HTML][HTML] Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

R Mazzone, C Zwergel, A Mai, S Valente - Clinical epigenetics, 2017 - Springer
Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or
cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal …

Immune checkpoint inhibitors in advanced non–small cell lung cancer

HI Assi, AO Kamphorst, NM Moukalled… - Cancer, 2018 - Wiley Online Library
The emergence of immune checkpoint inhibitors for the treatment of cancer has led to major
changes to the therapeutic landscape of lung cancer. Improvements in overall survival …

Theranostics using antibodies and antibody-related therapeutics

KL Moek, D Giesen, IC Kok, DJA de Groot… - Journal of Nuclear …, 2017 - Soc Nuclear Med
In theranostics, radiolabeled compounds are used to determine a treatment strategy by
combining therapeutics and diagnostics in the same agent. Monoclonal antibodies (mAbs) …

[HTML][HTML] Comprehensive analysis of the tumor immune micro-environment in non-small cell lung cancer for efficacy of checkpoint inhibitor

JS Seo, A Kim, JY Shin, YT Kim - Scientific reports, 2018 - nature.com
Characterizing the molecular immune subtype and micro-environment of lung cancer is
necessary to understand immunogenic interactions between infiltrating immune and stromal …

Predictors for clinical benefit of immune checkpoint inhibitors in advanced non-small-cell lung cancer: a meta-analysis

H El-Osta, S Jafri - Immunotherapy, 2019 - Taylor & Francis
Aim: In this meta-analysis, we evaluated several predictors of benefit to single-agent
immune checkpoint inhibitors (ICIs) in metastatic non-small-cell lung cancer (NSCLC) …

Predictability of Neutrophile to Lymphocyte Ratio and Platelet to Lymphocyte Ratio on the Effectiveness of Immune Checkpoint Inhibitors in Non-small Cell Lung …

CTT Nguyen, TNK Van, PT Huong - Cancer Control, 2024 - journals.sagepub.com
Objectives The associations between the neutrophil-lymphocyte ratio (NLR) and platelet-to-
lymphocyte ratio (PLR) with the responses of non-small cell lung cancer (NSCLC) patients …

[HTML][HTML] Biological bases of immune-related adverse events and potential crosslinks with immunogenic effects of radiation

L Bardoscia, N Pasinetti, L Triggiani, S Cozzi… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors have gained an established role in the treatment of different
tumors. Indeed, their use has dramatically changed the landscape of cancer care, especially …

[HTML][HTML] Naturally-occurring canine invasive urothelial carcinoma harbors luminal and basal transcriptional subtypes found in human muscle invasive bladder cancer

D Dhawan, NM Hahn, JA Ramos-Vara… - PLoS genetics, 2018 - journals.plos.org
There is growing evidence that molecular subtypes (eg luminal and basal subtypes) affect
the prognosis and treatment response in patients with muscle invasive urinary bladder …

[HTML][HTML] Comprehensive immune transcriptomic analysis in bladder cancer reveals subtype specific immune gene expression patterns of prognostic relevance

R Ren, K Tyryshkin, CH Graham, M Koti, DR Siemens - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recent efforts on genome wide profiling of muscle invasive bladder cancer (MIBC) have led
to its classification into distinct genomic and transcriptomic molecular subtypes that exhibit …