Therapeutic options in hepatocellular carcinoma: a comprehensive review

D Suresh, AN Srinivas, A Prashant… - Clinical and …, 2023 - Springer
Hepatocellular carcinoma (HCC) is a chronic liver disease that is highly fatal if not detected
and treated early. The incidence and death rate of HCC have been increasing in recent …

[HTML][HTML] Immunotherapy for advanced hepatocellular carcinoma, where are we?

L Zhang, J Ding, HY Li, ZH Wang, J Wu - Biochimica et Biophysica Acta …, 2020 - Elsevier
A couple of molecular-targeting medications, such as Lenvatinib, are available for the
treatment of hepatocellular carcinoma (HCC) in addition to Sorafenib in an advanced stage …

Messenger RNA electroporated hepatitis B virus (HBV) antigen-specific T cell receptor (TCR) redirected T cell therapy is well-tolerated in patients with recurrent HBV …

F Yang, X Zheng, S Koh, J Lu, J Cheng, P Li… - Hepatology …, 2023 - Springer
Background and aims Liver transplantation (LT) is the primary curative option for cirrhotic
patients with early-stage hepatocellular carcinoma (HCC). However, tumor recurrence …

[HTML][HTML] Thermal ablation and immunotherapy for hepatocellular carcinoma: Recent advances and future directions

XW Bo, LP Sun, SY Yu, HX Xu - World Journal of Gastrointestinal …, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of most common cancers that cause death in the
world. Thermal ablation (TA) is an important alternative treatment method for HCC patients …

Atypical immunometabolism and metabolic reprogramming in liver cancer: Deciphering the role of gut microbiome

RM Golonka, M Vijay-Kumar - Advances in cancer research, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide. Much recent research has delved into understanding the underlying molecular …

[HTML][HTML] Optimal timing of combining sorafenib with trans-arterial chemoembolization in patients with hepatocellular carcinoma: a meta-analysis

Y Dai, H Jiang, H Jiang, S Zhao, X Zeng, R Sun… - Translational …, 2021 - Elsevier
Background The combination therapy of trans-arterial chemoembolization (TACE) and
sorafenib were proved to be one of the effective methods for intermediate and advanced …

Natural killer cells and type 1 innate lymphoid cells in hepatocellular carcinoma: Current knowledge and future perspectives

N Jacquelot, C Seillet… - International Journal of …, 2021 - mdpi.com
Natural killer (NK) cells and type 1 innate lymphoid cells (ILC1) are specific innate lymphoid
cell subsets that are key for the detection and elimination of pathogens and cancer cells. In …

[PDF][PDF] Immunological characterization of hepatocellular carcinoma

SZ Wang, SD Lee, D Sarkar, HM Lee, A Khan… - Hepatoma …, 2021 - academia.edu
Hepatocellular carcinoma (HCC) is the most common type of primary liver malignancy and
the fourth leading cause of cancer-related deaths globally. HCC is often diagnosed in late …

[HTML][HTML] ImmunoPET imaging of CD38 expression in hepatocellular carcinoma using 64Cu-labeled daratumumab

S Li, CG England, EB Ehlerding… - American Journal of …, 2019 - ncbi.nlm.nih.gov
CD38 is expressed on the surface of many immune cells, which are closely associated with
antitumor immunity and immune tolerance of tumor cells. Therefore, monitoring CD38 …

PPIH as a poor prognostic factor increases cell proliferation and m6A RNA methylation in hepatocellular carcinoma

XX Chi, P Ye, NQ Cao, WL Hwang… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
RNA-binding proteins (RBPs) play a crucial role in the biological processes of liver
hepatocellular carcinoma (LIHC). Peptidyl-prolyl cis-trans isomerase H (PPIH), an RBP …