[HTML][HTML] Host Innate Antiviral Response to Influenza A Virus Infection: From Viral Sensing to Antagonism and Escape
W An, S Lakhina, J Leong, K Rawat, M Husain - Pathogens, 2024 - mdpi.com
Influenza virus possesses an RNA genome of single-stranded, negative-sensed, and
segmented configuration. Influenza virus causes an acute respiratory disease, commonly …
segmented configuration. Influenza virus causes an acute respiratory disease, commonly …
[HTML][HTML] HOIL1 mediates MDA5 activation through ubiquitination of LGP2
The RIG-I-like receptors (RLRs), RIG-I and MDA5, are innate sensors of RNA virus infections
that are critical for mounting a robust antiviral immune response. We have shown previously …
that are critical for mounting a robust antiviral immune response. We have shown previously …
Observation of Higher-Order Assemblies Controlled by Protein One-dimensional Movement
XP Han, M Rao, SR Wu, Q Zhang, F Hou, SQ Zhang… - bioRxiv, 2024 - biorxiv.org
RIG-I-like receptors (RLRs) detect cytosolic viral RNAs and initiate innate immune response.
MDA5 is an RLR that recognizes viral long double-stranded RNA (dsRNA). The central …
MDA5 is an RLR that recognizes viral long double-stranded RNA (dsRNA). The central …