Perinatal hyperoxia and developmental consequences on the lung‐brain axis

S Obst, J Herz, MA Alejandre Alcazar… - Oxidative medicine …, 2022 - Wiley Online Library
Approximately 11.1% of all newborns worldwide are born preterm. Improved neonatal
intensive care significantly increased survival rates over the last decades but failed to …

Acquired resistance to targeted therapies in NSCLC: Updates and evolving insights

CB Meador, AN Hata - Pharmacology & therapeutics, 2020 - Elsevier
While significant advancements have been made in the available therapies for metastatic
non-small cell lung cancer (NSCLC), acquired resistance remains a major barrier to …

[HTML][HTML] Pharmacotherapy in bronchopulmonary dysplasia: what is the evidence?

RP Sakaria, R Dhanireddy - Frontiers in Pediatrics, 2022 - frontiersin.org
Bronchopulmonary Dysplasia (BPD) is a multifactorial disease affecting over 35% of
extremely preterm infants born each year. Despite the advances made in understanding the …

[HTML][HTML] Vascular endothelial growth factor as molecular target for bronchopulmonary dysplasia prevention in very low birth weight infants

S Perrone, S Manti, L Buttarelli, C Petrolini… - International Journal of …, 2023 - mdpi.com
Bronchopulmonary dysplasia (BPD) still represents an important burden of neonatal care.
The definition of the disease is currently undergoing several revisions, and, to date, BPD is …

[HTML][HTML] Role of endoplasmic reticulum stress in impaired neonatal lung growth and bronchopulmonary dysplasia

KA Pritchard Jr, X Jing, M Teng, C Wells, S Jia… - Plos one, 2022 - journals.plos.org
Myeloperoxidase (MPO), oxidative stress (OS), and endoplasmic reticulum (ER) stress are
increased in the lungs of rat pups raised in hyperoxia, an established model of …

Nutrition-based implications and therapeutics in the development and recovery of bronchopulmonary dysplasia

A Heras, R Chambers, Z Solomon, L Blatt… - Seminars in …, 2023 - Elsevier
Premature births account for over 10% of live births worldwide. Bronchopulmonary dysplasia
(BPD) represents a severe sequela in neonates born very prematurely and remains the most …

Bronchopulmonary dysplasia predicted at birth by artificial intelligence

H Verder, C Heiring, R Ramanathan… - Acta …, 2021 - Wiley Online Library
Aim To develop a fast bedside test for prediction and early targeted intervention of
bronchopulmonary dysplasia (BPD) to improve the outcome. Methods In a multicentre study …

[HTML][HTML] Metabolic dysregulation in bronchopulmonary dysplasia: Implications for identification of biomarkers and therapeutic approaches

L Yue, X Lu, PA Dennery, H Yao - Redox Biology, 2021 - Elsevier
Bronchopulmonary dysplasia (BPD) is a common chronic lung disease in premature infants.
Accumulating evidence shows that dysregulated metabolism of glucose, lipids and amino …

[HTML][HTML] Allogeneic administration of human umbilical cord-derived mesenchymal stem/stromal cells for bronchopulmonary dysplasia: preliminary outcomes in four …

LT Nguyen, TTH Trieu, HTH Bui, VT Hoang… - Journal of Translational …, 2020 - Springer
Background Bronchopulmonary dysplasia (BPD) is a severe condition in premature infants
that compromises lung function and necessitates oxygen support. Despite major …

[HTML][HTML] Upregulating carnitine palmitoyltransferase 1 attenuates hyperoxia-induced endothelial cell dysfunction and persistent lung injury

JL Chang, J Gong, S Rizal, AL Peterson, J Chang… - Respiratory …, 2022 - Springer
Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease in premature
infants that may cause long-term lung dysfunction. Accumulating evidence supports the …