Murine models of obesity

T Martins, C Castro-Ribeiro, S Lemos, T Ferreira… - Obesities, 2022 - mdpi.com
Obesity, classified as an epidemic by the WHO, is a disease that continues to grow
worldwide. Obesity results from abnormal or excessive accumulation of fat and usually leads …

Recent advances in neuropeptide-related omics and gene editing: Spotlight on NPY and somatostatin and their roles in growth and food intake of fish

X Yu, H Yan, W Li - Frontiers in Endocrinology, 2022 - frontiersin.org
Feeding and growth are two closely related and important physiological processes in living
organisms. Studies in mammals have provided us with a series of characterizations of …

A peptide triple agonist of GLP-1, neuropeptide Y1, and neuropeptide Y2 receptors promotes glycemic control and weight loss

KS Chichura, CT Elfers, TS Salameh, V Kamat… - Scientific reports, 2023 - nature.com
Mechanisms underlying long-term sustained weight loss and glycemic normalization after
obesity surgery include changes in gut hormone levels, including glucagon-like peptide 1 …

A maternal high-fat diet causes anxiety-related behaviors by altering neuropeptide Y1 receptor and hippocampal volumes in rat offspring: The potential effect of N …

KK Tüfekci, EG Bakirhan, F Terzi - Molecular Neurobiology, 2023 - Springer
The children of obese mothers are known to have a high risk of obesity and metabolic
disease and are prone to developing cognitive deficits, although the underlying mechanism …

Hypothalamic NPY-Y1R interacts with gonadal hormones in protecting female mice against obesity and neuroinflammation

A Oberto, I Bertocchi, A Longo, S Bonzano… - International Journal of …, 2022 - mdpi.com
We previously demonstrated that Npy1r rfb mice, which carry the conditional inactivation of
the Npy1r gene in forebrain principal neurons, display a sexually dimorphic phenotype, with …

Методы машинного обучения и анализа больших данных для установления молекулярных механизмов воздействия рацетамов на метаболизм жировой …

ИЮ Торшин, ОА Громова, ЛБ Лазебник - Экспериментальная и …, 2024 - nogr.org
Аннотация Рацетамы проявляют не только ноотропные эффекты, но и влияют на
обмен жиров и углеводов. Экспериментальные исследования указали на возможность …

Effetti dell'ambiente materno precoce e dell'espressione di NPY-1r in area limbica su comportamento e riproduzione di topi femmine KO condizionali

G Ramundo - 2022 - iris.unimore.it
The phenotype is the set of morphological and functional traits of an organism, resulting from
the interaction between genotype and environmental factors. In mammals, early maternal …