Core transcriptional circuitry in human cells and methods of use thereof

V Saint-Andre, BJ Abraham, ZP Fan, TI Lee… - US Patent …, 2022 - Google Patents
US11319591B2 - Core transcriptional circuitry in human cells and methods of use thereof -
Google Patents US11319591B2 - Core transcriptional circuitry in human cells and methods of …

Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists

MW Chen, C Collins, ML Eaton, MG Guenther… - US Patent …, 2020 - Google Patents
The invention provides methods that define cellular populations that are sensitive to RARA
agonists and identify patient subgroups that will benefit from treatment with RARA agonists …

Methods of stratifying patients for treatment with retinoic acid receptor-α agonists

MR McKeown, C Fiore, ML Eaton, EP Lee… - US Patent …, 2021 - Google Patents
US11053552B2 - Methods of stratifying patients for treatment with retinoic acid receptor-α
agonists - Google Patents US11053552B2 - Methods of stratifying patients for treatment with …

Super-enhancers and methods of use thereof

D Hnisz, B Abraham, TI Lee, RA Young - US Patent 10,160,977, 2018 - Google Patents
The present invention relates in some aspects to super-enhancers and related
compositions, methods, and agents that are useful for modulating expression of cell type …

Methods of stratifying patients for treatment with retinoic acid receptor-agonists

MW CHEN, C COLLINS, ML EATON, MG Guenther… - 2021 - Google Patents
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(O)= O)= O Chemical compound CC (C)(CCC (C)(C) c1c2) c1ccc2NC (c (cc1) ccc1C (O) …

Methods of stratifying patients for treatment with retinoic acid receptor-alpha agonists

MW Chen, C Collins, ML Eaton, MG Guenther… - US Patent …, 2022 - Google Patents
The invention provides methods that define cellular populations that are sensitive to RARA
agonists and identify patient subgroups that will benefit from treatment with RARA agonists …

Rara agonists for the treatment of aml and mds

MR MCKEOWN, C FIORE, ML EATON, EP LEE, C Fritz - 2017 - Google Patents
WO2017177167A1 - Rara agonists for the treatment of aml and mds - Google Patents
WO2017177167A1 - Rara agonists for the treatment of aml and mds - Google Patents Rara …

METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH RETINOIC ACID RECEPTOR-α AGONISTS

MW CHEN, C COLLINS, ML EATON, MG Guenther… - 2016 - Google Patents
WO2016161107A1 - METHODS OF STRATIFYING PATIENTS FOR TREATMENT WITH
RETINOIC ACID RECEPTOR-α AGONISTS - Google Patents WO2016161107A1 …