The immunopathogenesis of Alzheimer's disease is related to the composition of gut microbiota
F Leblhuber, D Ehrlich, K Steiner, S Geisler, D Fuchs… - Nutrients, 2021 - mdpi.com
The microbiota–gut–brain axis plays an important role in the development of
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …
neurodegenerative diseases. Commensal and pathogenic enteric bacteria can influence …
Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease
Alzheimer's disease (AD) is the most common dementing disorder of late life. Although there
might be various different triggering events in the early stages of the disease, they seem to …
might be various different triggering events in the early stages of the disease, they seem to …
Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration
E Rojas‐Gutierrez, G Muñoz‐Arenas, S Treviño… - Synapse, 2017 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia and one of the most
important causes of morbidity and mortality among the aging population. AD diagnosis is …
important causes of morbidity and mortality among the aging population. AD diagnosis is …
The physiologic response and associated clinical benefits from provision of early enteral nutrition
SA McClave, DK Heyland - Nutrition in Clinical Practice, 2009 - Wiley Online Library
Provision of enteral nutrition (EN) to critically ill patients early upon admission to the
intensive care unit exerts a beneficial physiologic effect that downregulates systemic …
intensive care unit exerts a beneficial physiologic effect that downregulates systemic …
Advanced glycation endproducts and their pathogenic roles in neurological disorders
G Münch, B Westcott, T Menini, A Gugliucci - Amino acids, 2012 - Springer
Glycation is implicated in neurological disorders. In some cases it plays a key role in the
pathogenesis, in others it plays a co-adjuvant role or it appears as a consequence of …
pathogenesis, in others it plays a co-adjuvant role or it appears as a consequence of …
Macrophages and diabetic nephropathy
GH Tesch - Seminars in Nephrology, 2010 - Elsevier
Evidence from renal biopsies has shown that macrophage accumulation in diabetic kidneys
predicts declining renal function, suggesting a pathogenic role for these cells in diabetic …
predicts declining renal function, suggesting a pathogenic role for these cells in diabetic …
Advanced glycation end products and lipopolysaccharides stimulate interleukin‑6 secretion via the RAGE/TLR4‑NF‑κB‑ROS pathways and resveratrol attenuates …
A Ohtsu, Y Shibutani, K Seno… - Experimental and …, 2017 - spandidos-publications.com
Macrophages are essential for regulating the physiology of pregnancy; however, excessive
inflammatory responses to macrophages, induced by infection and/or endogenous danger …
inflammatory responses to macrophages, induced by infection and/or endogenous danger …
Reprint of “Accumulation of modified proteins and aggregate formation in aging”
K Nowotny, T Jung, T Grune, A Höhn - Experimental gerontology, 2014 - Elsevier
Increasing cellular damage during the aging process is considered to be one factor limiting
the lifespan of organisms. Besides the DNA and lipids, proteins are frequent targets of non …
the lifespan of organisms. Besides the DNA and lipids, proteins are frequent targets of non …
Methylglyoxal, cognitive function and cerebral atrophy in older people
V Srikanth, B Westcott, J Forbes… - … Series A: Biomedical …, 2013 - academic.oup.com
Background. The effects of advanced glycation endproducts on cognition and brain structure
are poorly understood. We studied associations of the advanced glycation endproduct …
are poorly understood. We studied associations of the advanced glycation endproduct …
Microglia, Alzheimer′ s Disease, and Complement
H Crehan, J Hardy, J Pocock - International Journal of …, 2012 - Wiley Online Library
Microglia, the immune cell of the brain, are implicated in cascades leading to neuronal loss
and cognitive decline in Alzheimer's disease (AD). Recent genome‐wide association …
and cognitive decline in Alzheimer's disease (AD). Recent genome‐wide association …