A unified hypothesis of SUDEP: Seizure‐induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and …

CL Faingold, HJ Feng - Epilepsia, 2023 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in people with
epilepsy (PWE). Postictal apnea leading to cardiac arrest is the most common sequence of …

Prevention of sudden unexpected death in epilepsy: current status and future perspectives

MC Pensel, RD Nass, E Taubøll, D Aurlien… - Expert Review of …, 2020 - Taylor & Francis
Introduction: Sudden unexpected death in epilepsy (SUDEP) affects about 1 in 1000 people
with epilepsy, and even more in medically refractory epilepsy. As most people are between …

An exploratory study on the association between serotonin and sleep breathing disorders

M Wieckiewicz, H Martynowicz, G Lavigne… - Scientific Reports, 2023 - nature.com
This exploratory observational study aimed to evaluate whether the blood levels of serotonin
and enzymes involved in serotonin synthesis are associated with sleep breathing …

Serotonin 5-HT4 receptors play a critical role in the action of fenfluramine to block seizure-induced sudden death in a mouse model of SUDEP

S Tupal, CL Faingold - Epilepsy research, 2021 - Elsevier
Rationale Our previous study showed that the recently approved anticonvulsant drug,
fenfluramine, which enhances the release of serotonin (5-hydroxytryptamine, 5-HT) in the …

A narrative review of the mechanisms and consequences of intermittent hypoxia and the role of advanced analytic techniques in pediatric autonomic disorders

JM Ramirez, MS Carroll, N Burgraff, CM Rand… - Clinical Autonomic …, 2023 - Springer
Disorders of autonomic functions are typically characterized by disturbances in multiple
organ systems. These disturbances are often comorbidities of common and rare diseases …

Sudden unexpected death in epilepsy in children

R Whitney, S Sharma… - … Medicine & Child …, 2023 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy‐related
mortality in children and adults living with epilepsy. The incidence of SUDEP is comparable …

Neuropathology findings in autonomic brain regions in SUDEP and future research directions

S Patodia, A Somani, M Thom - Autonomic Neuroscience, 2021 - Elsevier
Autonomic dysfunction is implicated from clinical, neuroimaging and experimental studies in
sudden and unexpected death in epilepsy (SUDEP). Neuropathological analysis in SUDEP …

Advances in sudden unexpected death in epilepsy

H Zhao, L Long, B Xiao - Acta Neurologica Scandinavica, 2022 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is the major cause of premature death in
epilepsy patients, particularly those with refractory epilepsy. Sudden unexpected death in …

Sudden unexpected death in epilepsy

D Friedman - Current Opinion in Neurology, 2022 - journals.lww.com
Sudden unexpected death in epilepsy : Current Opinion in Neurology Sudden unexpected
death in epilepsy : Current Opinion in Neurology Log in or Register Subscribe to journalSubscribe …

Serotonin transporter in the temporal lobe, hippocampus and amygdala in SUDEP

S Patodia, A Somani, J Liu, A Cattaneo… - Brain …, 2022 - Wiley Online Library
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment
with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for …