Synthesis and anticancer activity of some new fused pyrazoles and their glycoside derivatives

IF Nassar, AF El Farargy… - Journal of Heterocyclic …, 2018 - Wiley Online Library
4‐(4‐Chlorobenzylidene)‐2, 5‐diphenyl‐2, 3‐dihydro‐3H‐pyrazol‐3‐one 3a and 4‐(3, 4‐
dimethoxybenzylidene)‐5‐phenyl‐2, 3‐dihydro‐3H‐pyrazol‐3‐one 3b were prepared and …

Design, Synthesis, and Anticancer Activity of New Oxadiazolyl‐Linked and Thiazolyl‐Linked Benzimidazole Arylidines, Thioglycoside, and Acyclic Analogs

IF Nassar, DS El Kady, HM Awad… - Journal of Heterocyclic …, 2019 - Wiley Online Library
2‐[(4‐Thiazolylmethyl) thio]‐1H‐benzimidazole 3 was prepared and was allowed to react
with ethyl chloroactate then with hydrazine hydrate to afford the hydrazide derivative 5 …

Synthesis of Novel Phthalazine Derivatives as Potential Anticancer and Antioxidant Agents Based on 1‐Chloro‐4‐(4‐phenoxyphenyl) phthalazine

MS Behalo, IA Gad El‐karim… - Journal of Heterocyclic …, 2017 - Wiley Online Library
A new series of phthalazine derivatives was synthesized from the reaction of 1‐chloro‐4‐(4‐
phenoxyphenyl) phthalazine as a reactive starting material with different carbon, nitrogen …

Synthesis and Antimicrobial Activity of 1, 3, 4-Oxadiazoline, 1, 3-Thiazolidine, and 1, 2, 4-Triazoline Double-Tailed Acyclo C-Nucleosides

AZ Nasr, A Farahat, MA Zein, ESM Abdelrehim - ACS omega, 2022 - ACS Publications
The condensation products of terphthaloyl bishydrazide with two equivalents of various
monosaccharide aldoses were found to have a bis (sugarhydrazone) form or bis …

Synthesis and Antibacterial Activity of Some Derivatives of 2‐Methylbenzimidazole Containing 1, 3, 4‐Oxadiazole or 1, 2, 4‐Triazole Heterocycle

C Nguyen Tien, D Tran Thi Cam… - Journal of …, 2016 - Wiley Online Library
5‐[(2‐Methyl‐1H‐benzimidazol‐1‐yl) methyl]‐1, 3, 4‐oxadiazole‐2‐thiol or 5‐[(2‐methyl‐1H‐
benzimidazol‐1‐yl) methyl]‐4‐(4‐methylphenyl)‐1, 2, 4‐triazol‐3‐thiol which were prepared …

Synthesis and quantitative structure activity relationship (QSAR) of arylidene (benzimidazol-1-yl) acetohydrazones as potential antibacterial agents

Y El-Kilany, NM Nahas, MA Al-Ghamdi… - World Journal of …, 2015 - Springer
Abstract Ethyl (benzimidazol-1-yl) acetate was subjected to hydrazinolysis with hydrazine
hydrate to give (benzimidazol-1-yl) acetohydrazide. The latter was reacted with various …

Synthesis of new furanone derivatives with potent anticancer activity

WH Lashin, IF Nassar, AF El Farargy… - Russian Journal of …, 2020 - Springer
New compounds based on Furanone derivatives were synthesized by reaction of 3-(4-
nitrobezylidine)-5-phenylfuran-2 (3 H)-one with various reagents as malononitrile then D …

[PDF][PDF] Month 2017 Synthesis of Novel Phthalazine Derivatives as Potential Anticancer and Antioxidant Agents Based on 1-Chloro-4-(4-phenoxyphenyl) phthalazine

MS Behalo, IAG El-karim, R Rafaat - 2017 - researchgate.net
Phthalazine derivatives have been the subject of extensive studies in the past years. Among
these phthalazines, 4-substituted phthalazines act as effective anti-inflammatory [1, 2] …