The cytoskeleton and its components—actin, microtubules and intermediate filaments—
have been studied for decades, and multiple roles of the individual cytoskeletal …

Mitotic spindle orientation is essential for cell fate decisions, epithelial maintenance, and
tissue morphogenesis. In most animal cell types, the dynein motor complex is anchored at …

Proper patterning of the nervous system requires that developing axons find appropriate
postsynaptic partners; this entails microns to meters of extension through an extracellular …

Many aspects of cytoskeletal assembly and dynamics can be recapitulated in vitro; yet, how
the cytoskeleton integrates signals in vivo across cellular membranes is far less understood …

The tumor microenvironment (TME) is a dynamic and complex matter shaped by
heterogenous cancer and cancer‐associated cells present at the tumor site. Hyaluronan …

Crosstalk between the actin cytoskeleton and microtubules promotes symmetry break to
polarize cells for division, shape changes, and migration. These cellular events are crucial …

The preparation of eukaryotic cells for division requires an extensive cellular reorganization,
affecting cytoskeletal elements, chromatin, and organelles. These drastic changes in cellular …

Invadopodia are actin-rich protrusions that degrade the extracellular matrix and are required
for stromal invasion, intravasation, and metastasis. The role of the focal adhesion protein …

The cell cortex is a dynamic and heterogeneous structure that governs cell identity and
behavior. The ERM proteins (ezrin, radixin and moesin) are major architects of the cell …

PIWI-interacting RNAs (piRNAs) are thought to silence transposon and gene expression
during development. However, the roles of piRNAs in somatic tissues are largely unknown …