[HTML][HTML] Complex interplay between autophagy and oxidative stress in the development of pulmonary disease

W Ornatowski, Q Lu, M Yegambaram, AE Garcia… - Redox biology, 2020 - Elsevier
The autophagic pathway involves the encapsulation of substrates in double-membraned
vesicles, which are subsequently delivered to the lysosome for enzymatic degradation and …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos - Pharmacological reviews, 2017 - ASPET
Over the last decade, hydrogen sulfide (H2S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Environment-triggered nanoagent with programmed gas release performance for accelerating diabetic infected wound healing

Y Xu, J Jiang, X Lv, H Li, D Yang, W Wang, Y Hu… - Chemical Engineering …, 2024 - Elsevier
The treatment of diabetic infected wound still faces severe challenges, including drug-
resistant bacterial infections, exaggerated inflammatory reactions, and dysangiogenesis. To …

Hydrogen sulfide biology and its role in cancer

S Khattak, MA Rauf, NH Khan, QQ Zhang, HJ Chen… - Molecules, 2022 - mdpi.com
Hydrogen sulfide (H2S) is an endogenous biologically active gas produced in mammalian
tissues. It plays a very critical role in many pathophysiological processes in the body. It can …

Roles of hydrogen sulfide in the pathogenesis of diabetes mellitus and its complications

C Szabo - Antioxidants & redox signaling, 2012 - liebertpub.com
Significance: Diabetes and its complications represent a major socioeconomic problem.
Recent Advances: Changes in the balance of hydrogen sulfide (H2S) play an important role …

The role of nuclear factor-erythroid 2 related factor 2 (Nrf-2) in the protection against lung injury

H Zhao, S Eguchi, A Alam, D Ma - American Journal of …, 2017 - journals.physiology.org
Nuclear factor-erythroid 2 related factor 2 (Nrf2) is a ubiquitous master transcription factor
that upregulates antioxidant response elements (AREs)-mediated expression of antioxidant …

Emerging role of hydrogen sulfide in hypertension and related cardiovascular diseases

G Meng, Y Ma, L Xie, A Ferro… - British journal of …, 2015 - Wiley Online Library
Hydrogen sulfide (H2S) has traditionally been viewed as a highly toxic gas; however, recent
studies have implicated H2S as a third member of the gasotransmitter family, exhibiting …

Hydrogen sulfide offers neuroprotection on traumatic brain injury in parallel with reduced apoptosis and autophagy in mice

M Zhang, H Shan, P Chang, T Wang, W Dong, X Chen… - PloS one, 2014 - journals.plos.org
Hydrogen sulfide (H2S), a novel gaseous mediator, has been recognized as an important
neuromodulator and neuroprotective agent in the central nervous system. The present study …

The role of hydrogen sulfide in respiratory diseases

S Khattak, QQ Zhang, M Sarfraz, P Muhammad… - Biomolecules, 2021 - mdpi.com
Respiratory diseases are leading causes of death and disability around the globe, with a
diverse range of health problems. Treatment of respiratory diseases and infections has been …