Babies who are small at birth or during infancy have increased rates of cardiovascular
disease and non-insulin-dependent diabetes as adults. Some of these babies have low …

In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

To examine the relationship between growth hormone (GH) and insulin-like growth factor 1
(IGF1) in controlling postnatal growth, we performed a comparative analysis of dwarfing …

Laron syndrome [growth hormone (GH) insensitivity syndrome] is a hereditary dwarfism
resulting from defects in the GH receptor (GHR) gene. GHR deficiency has not been …

GH participates in growth, metabolism, and cellular differentiation. To study these roles, we
previously generated two different dwarf mouse lines, one expressing a GH antagonist …

The somatotropic axis, consisting of growth hormone (GH), hepatic insulin‐like growth factor
I (IGF‐I), and assorted releasing factors, regulates growth and body composition …

In mammals, secretin is a 27-amino acid peptide that was first studied in 1902 by Bayliss
and Starling from the extracts of the jejunal mucosa for its ability to stimulate pancreatic …

Data obtained while investigating growth plate chondrocyte differentiation during
endochondral bone formation both in vivo and in vitro indicate that initial chondrogenesis …

There is literature evidence that both growth hormone (GH) and its mediator, insulin-like
growth factor 1 (IGF-1), are able to act upon neuronal and glial cells in the brain. We report …

Once thought to be present only in liver, muscle and adipose tissue, the GH receptor is now
known to be ubiquitously distributed, in accord with the many pleiotropic actions of GH …