[PDF][PDF] L-asparaginase and L-glutaminase: sources, production, and applications in medicine and industry

HM Orabi, EM El-Fakharany… - The Journal of …, 2019 - pdfs.semanticscholar.org
L-asparaginase and L-glutaminase are members of homologous amidohydrolase enzymes,
which hydrolyze asparagine and glutamine into their acids and ammonia. Enzymes are very …

Response surface methodology based optimized production, purification, and characterization of L-asparaginase from Fusarium foetens

J Parashiva, BR Nuthan, M Bharatha… - World Journal of …, 2023 - Springer
L-asparaginase is used as one of the prime chemotherapeutic agents to treat acute
lymphoblastic leukemia. L-asparaginase obtained from bacteria exhibits hypersensitive …

A new extracellular glutaminase and urease-free l-asparaginase from Meyerozyma guilliermondii

A Ratuchne, SC Izidoro, SM Beitel, LT Lacerda… - Brazilian Journal of …, 2023 - Springer
Abstract l-Asparaginase (l-ASNase) is a potent chemotherapeutic drug employed to treat
leukemia and lymphoma. Currently, l-ASNases for therapeutic use are obtained from …

Computational modeling of culture media for enhanced production of fibrinolytic enzyme from marine bacterium Fictibacillus sp. strain SKA27 and in vitro evaluation …

K Joji, A Santhiagu, N Salim - 3 Biotech, 2019 - Springer
The present study reports the optimized production and purification of an extremely active
fibrinolytic enzyme from newly isolated marine bacterium Fictibacillus sp. strain SKA27, with …

Caracterización bioinformática y producción de L-asparaginasa de Bacillus sp. M62 aislado de las salinas de Maras, Cusco, Perú

Y Tapia-Bañez, K Jiménez-Aliaga… - Revista peruana de …, 2023 - scielo.org.pe
El objetivo del estudio fue realizar la caracterización bioinformática, así como optimizar la
producción de L-asparaginasa extracelular de Bacillus sp. M62 aislada de las salinas de …

Development of a downstream process for purification and purity analysis of glutaminase free L-asparaginase using UPLC, DLS-ZP and DSC-TGA

P Prakash, S Chandrayan, P Tiwari… - Journal of Taibah …, 2021 - Taylor & Francis
Several bacterial strains were isolated from soil and water in the current work and screened
for glutaminase-free L-asparaginase activity. The selected strain was subjected to the …

Microbial Asparaginase and Its Bioprocessing Significance

S Calderón‐Toledo, AI Zavaleta… - Microbial Bioreactors …, 2023 - Wiley Online Library
Summary l‐Asparaginase hydrolyzes l‐asparagine to l‐aspartic acid and releases
ammonium in a two‐step process, which is used in the treatment of leukemia. In this regard …

Exteracellular l-asparaginase from local soil bacteria: Production and optimization of physiological condition

HM Orabi, EM El-Fakrany, ES Abdel Khalek… - Al-Azhar Bulletin of …, 2018 - journals.ekb.eg
L-asparaginase produced by Bacillushalotolerans OHEM18 finds broad applications due to
its hydrolysis activity so used as therapeutic agents in combination with additional …

[PDF][PDF] Hanaa Mahmoud Orabi', Esmail Mohammed El-Fakrany", Eman Shawky Abdel Khalek', Aziza M. EI-Kasaby" Nagwa Mahmoude Sidkey"

ELAF LOCAL - researchgate.net
ABSTRACT L-asparaginase produced by Bacillushalotolerans OHEM18 finds broad
applications due to its hydrolysis activity so used as therapeutic agents in combination with …

[PDF][PDF] Bioscience Research

DM Ahmed, HAH Zahran, FA Zaher - 2003 - isisn.org
The influence of calcium sources on the post-harvest performance of gladiolus cut flowers
was evaluated by applying 200 mM calcium from various sources (calcium chloride, calcium …