Methods to specifically profile protease activity at lymph nodes

SN Bhatia, DJ Irvine, KD Wittrup, AD Warren… - US Patent …, 2022 - Google Patents
In some aspects, the disclosure provides compositions and methods for detecting and
monitoring the activity of pro teases in vivo using affinity assays. The disclosure relates, in …

Methods to spatially profile protease activity in tissue and sections

SN Bhatia, JS Dudani, EJ Kwon… - US Patent 11,519,905, 2022 - Google Patents
Aspects of the disclosure relate to methods and composi tions useful for in vivo and/or in
vitro enzyme profiling. In some embodiments, the disclosure provides methods of in vivo …

Methods and products for in vivo enzyme profiling

SN Bhatia, GA Von Maltzahn, GA Kwong - US Patent 11,703,510, 2023 - Google Patents
The present invention relates to methods and products associated with in vivo enzyme
profiling. In particular, the invention relates to methods of in vivo processing of exogenous …

Methods and products for in vivo enzyme profiling

SN Bhatia, GA Von Maltzahn, GA Kwong - US Patent 11,549,951, 2023 - Google Patents
US11549951B2 - Methods and products for in vivo enzyme profiling - Google Patents
US11549951B2 - Methods and products for in vivo enzyme profiling - Google Patents …

Sensors for detecting and imaging of cancer metastasis

SN Bhatia, L Hao - US Patent 11,835,522, 2023 - Google Patents
2020-02-26 Assigned to MASSACHUSETTS INSTITUTE OF TECHNOLOGY reassignment
MASSACHUSETTS INSTITUTE OF TECHNOLOGY ASSIGNMENT OF ASSIGNORS …

Compositions, imaging, and therapeutic methods targeting folate receptor 1 (FOLR1)

HD Agnew, A Eliasen, BT Lai - US Patent 11,733,246, 2023 - Google Patents
The present application provides stable heterobiligands made up of peptide-based FOLR1
ligands and folate (the ligand of FOLR1) and methods of use of the heterobiligands as …

Botulinum neurotoxin-specific capture agents, compositions, and methods of using and making

B Farrow, JR Heath, HD Agnew - US Patent 11,723,944, 2023 - Google Patents
The present application provides stable peptide-based Botulinum neurotoxin (BoNT)
serotype A capture agents and methods of use as detection and diagnosis agents and in the …

Affinity-based detection of ligand-encoded synthetic biomarkers

SN Bhatia, DK Wood, GA Kwong, AD Warren… - US Patent …, 2024 - Google Patents
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IL-17F and IL-17A-specific capture agents, compositions, and methods of using and making

H Agnew, BT Lai, SM Pitram, B Farrow… - US Patent …, 2023 - Google Patents
US11719705B2 - IL-17F and IL-17A-specific capture agents, compositions, and methods of
using and making - Google Patents US11719705B2 - IL-17F and IL-17A-specific capture …

Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase 1 (IDO1) and methods of making and using same

BT Lai, HD Agnew - US Patent 11,884,707, 2024 - Google Patents
US11884707B2 - Compositions for detection, inhibition and imaging of indoleamine 2, 3-dioxygenase
1 (IDO1) and methods of making and using same - Google Patents US11884707B2 …