The study of homologous recombination has its historical roots in meiosis. In this context,
recombination occurs as a programmed event that culminates in the formation of crossovers …

The repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is
initiated by nucleolytic degradation of the 5′-terminated strands in a process termed end …

Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …

Meiosis, the mechanism of creating haploid gametes, is a complex cellular process
observed across sexually reproducing organisms. Fundamental to meiosis is the process of …

Recombination in meiosis is a fascinating case study for the coordination of chromosomal
duplication, repair, and segregation with each other and with progression through a cell …

During meiosis, homologous chromosomes undergo crossover recombination, which is
typically concentrated in narrow hot spots that are controlled by genetic and epigenetic …

DNA double-strand breaks that initiate meiotic recombination are exonucleolytically
processed. This 5′→ 3′ resection is a central, conserved feature of recombination but …

Programmed DNA double-strand break (DSB) formation is a crucial feature of meiosis in
most organisms. DSBs initiate recombination-mediated linking of homologous …

Meiosis is a specialized cell division program that is essential for sexual reproduction. The
two meiotic divisions reduce chromosome number by half, typically generating haploid …

Genetic recombination generates novel trait combinations, and understanding how
recombination is distributed across the genome is key to modern genetics. The PRDM9 …