Is there still hope for the prophylactic hepatitis C vaccine? A review of different approaches

P Rzymski, AT Jibril, L Rahmah… - Journal of Medical …, 2024 - Wiley Online Library
Despite remarkable progress in the treatment of hepatitis C virus (HCV) infection, it remains
a significant global health burden, necessitating the development of an effective prophylactic …

Role of NLRP3 inflammasome in nanoparticle adjuvant-mediated immune response

M Ahmed, P Kurungottu, K Swetha, S Atla… - Biomaterials …, 2024 - pubs.rsc.org
The nucleotide-binding oligomerization domain (NOD)-like receptor (NLR) family pyrin
domain-containing 3 (NLRP3) inflammasome is pivotal in orchestrating the immune …

Recent Progress in Cancer Vaccines and Nanovaccines

K Poudel, T Vithiananthan, JO Kim, H Tsao - Biomaterials, 2024 - Elsevier
Vaccine science, nanotechnology, and immunotherapy are at the forefront of cancer
treatment strategies, each offering significant potential for enhancing tumor-specific …

[HTML][HTML] Virus-Like Particles in Poultry Disease: An Approach to Effective and Safe Vaccination

AA Raji, PZ Dastjerdi, AR Omar - Frontiers in Veterinary Science, 2024 - frontiersin.org
The poultry industry, a cornerstone of global food security, faces dynamic challenges
exacerbated by viral diseases. This review traces the trajectory of poultry vaccination …

Advances in Nucleic Acid Universal Influenza Vaccines

L Xu, W Ren, Q Wang, J Li - Vaccines, 2024 - mdpi.com
Currently, vaccination with influenza vaccines is still an effective strategy to prevent infection
by seasonal influenza virus in spite of some drawbacks with them. However, due to the rapid …

Biomimetic nanoparticle-driven strategies for targeted drug delivery in glioblastoma

KN Panchal, S Mutalik, J Manikkath - Journal of Nanoparticle Research, 2024 - Springer
Glioblastoma (GBM), the most prevalent primary brain tumor in adults, remains highly
challenging due to its invasive nature, limited treatment effectiveness, and short median …

[HTML][HTML] Trends in Viral Vector-Based Vaccines for Tuberculosis: A Patent Review (2010–2023)

LC Santos, AMS Fernandes, IA Alves, MR Serafini… - Vaccines, 2024 - mdpi.com
Tuberculosis (TB) is an ancient global public health problem. Several strategies have been
applied to develop new and more effective vaccines against TB, from attenuated or …

DNA Vaccine Encoding a Modified Hemagglutinin Trimer of Avian Influenza A Virus H5N8 Protects Mice from Viral Challenge

VR Litvinova, AP Rudometov, NB Rudometova… - Vaccines, 2024 - mdpi.com
The development of a safe and effective vaccine against avian influenza A virus (AIV) H5N8
is relevant due to the widespread distribution of this virus in the bird population and the …

mRNA Vaccine for Alzheimer's Disease: Pilot Study

A Hovakimyan, G Chilingaryan, O King, JK Capocchi… - Vaccines, 2024 - mdpi.com
The escalating global healthcare challenge posed by Alzheimer's Disease (AD) and
compounded by the lack of effective treatments emphasizes the urgent need for innovative …

[HTML][HTML] Safety and Efficacy of Antiviral Drugs and Vaccines in Pregnant Women: Insights from Physiologically Based Pharmacokinetic Modeling and Integration of …

B Costa, MJ Gouveia, N Vale - Vaccines, 2024 - mdpi.com
Addressing the complexities of managing viral infections during pregnancy is essential for
informed medical decision-making. This comprehensive review delves into the management …