Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties
G Galati, PJ O'brien - Free radical biology and medicine, 2004 - Elsevier
Flavonoids, including isoflavones, are natural components in our diet and, with the
burgeoning interest in alternative medicine, are increasingly being ingested by the general …
burgeoning interest in alternative medicine, are increasingly being ingested by the general …
The role of flavonoids in autoimmune diseases: Therapeutic updates
Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …
and used to treat and/or manage human ailments such as metabolic, cardiovascular …
Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells
A Shvedova, V Castranova, E Kisin… - Journal of toxicology …, 2003 - Taylor & Francis
Carbon nanotubes are new members of carbon allotropes similar to fullerenes and graphite.
Because of their unique electrical, mechanical, and thermal properties, carbon nanotubes …
Because of their unique electrical, mechanical, and thermal properties, carbon nanotubes …
Topoisomerase II and leukemia
MJ Pendleton, RH Lindsey Jr, CA Felix… - Annals of the New …, 2014 - Wiley Online Library
Type II topoisomerases are essential enzymes that modulate DNA under‐and overwinding,
knotting, and tangling. Beyond their critical physiological functions, these enzymes are the …
knotting, and tangling. Beyond their critical physiological functions, these enzymes are the …
Tumor cell death induced by topoisomerase-targeting drugs
TK Li, LF Liu - Annual review of pharmacology and toxicology, 2001 - annualreviews.org
DNA topoisomerases are double-edged swords. They are essential for many vital functions
of DNA during normal cell growth. However, they are also highly vulnerable under various …
of DNA during normal cell growth. However, they are also highly vulnerable under various …
Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes
AR Murray, E Kisin, SS Leonard, SH Young… - Toxicology, 2009 - Elsevier
Single-walled carbon nanotubes (SWCNT) represent a novel material with unique electronic
and mechanical properties. The extremely small size (∼ 1nm diameter) renders their …
and mechanical properties. The extremely small size (∼ 1nm diameter) renders their …
Peroxidases
PJ O'Brien - Chemico-biological interactions, 2000 - Elsevier
The family of human peroxidases described includes myeloperoxidase, eosinophil
peroxidase, uterine peroxidase, lactoperoxidase, salivary peroxidase, thyroid peroxidase …
peroxidase, uterine peroxidase, lactoperoxidase, salivary peroxidase, thyroid peroxidase …
Deleterious effects of reactive metabolites
SM Attia - Oxidative medicine and cellular longevity, 2010 - Wiley Online Library
A number of drugs have been withdrawn from the market or severely restricted in their use
because of unexpected toxicities that become apparent only after the launch of new drug …
because of unexpected toxicities that become apparent only after the launch of new drug …
Enzymatic oxidative biodegradation of nanoparticles: Mechanisms, significance and applications
II Vlasova, AA Kapralov, ZP Michael, SC Burkert… - Toxicology and applied …, 2016 - Elsevier
Biopersistence of carbon nanotubes, graphene oxide (GO) and several other types of
carbonaceous nanomaterials is an essential determinant of their health effects. Successful …
carbonaceous nanomaterials is an essential determinant of their health effects. Successful …
Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells
S Tanigawa, M Fujii, DX Hou - Bioscience, biotechnology, and …, 2008 - academic.oup.com
There is evidence for defects in the mechanisms that allow the activation of p53 in many of
the cancers that retain wild-type p53. Reactivation of p53 has been suggested to be an …
the cancers that retain wild-type p53. Reactivation of p53 has been suggested to be an …