[HTML][HTML] The immunopathogenesis of sarcoidosis

J Miedema, F Cinetto, A Smed-Sörensen… - Journal of …, 2024 - Elsevier
Sarcoidosis is a granulomatous multiorgan disease, thought to result from exposure to yet
unidentified antigens in genetically susceptible individuals. The exaggerated inflammatory …

Th17. 1 lymphocytes: emerging players in the orchestra of immune-mediated inflammatory diseases

DP Misra, V Agarwal - Clinical Rheumatology, 2022 - Springer
It is now well established that Th17 lymphocytes associate with myriad immune-mediated
inflammatory diseases. Over the past one and a half decades, a subset of Th17 lymphocytes …

From COVID-19 to sarcoidosis: how similar are these two diseases?

M Zhao, C Tian, S Cong, X Di, K Wang - Frontiers in Immunology, 2022 - frontiersin.org
Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), leads to the dysregulation of the immune system …

[HTML][HTML] Systemic immune response to vimentin and granuloma formation in a model of pulmonary sarcoidosis

H Bagavant, K Cizio, AM Araszkiewicz… - Journal of translational …, 2022 - Elsevier
A characteristic feature of sarcoidosis is a dysregulated immune response to persistent
stimuli, often leading to the formation of non-necrotizing granulomas in various organs …

Treatment of Granulomatous Inflammation in Pulmonary Sarcoidosis

AK Gerke - Journal of clinical medicine, 2024 - mdpi.com
The management of pulmonary sarcoidosis is a complex interplay of disease characteristics,
the impact of medications, and patient preferences. Foremost, it is important to weigh the risk …

Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis

R Kraaijvanger, M Janssen Bonás, JC Grutters… - Respiratory …, 2024 - Springer
Background Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily
affecting the lungs. Treatment is needed when disease symptoms worsen and organ …

Efficacy and safety of Infliximab in systemic sarcoidosis according to GenPhenReSa organ-involvement phenotype: a retrospective study of 55 patients

E Rivière, W Jourde, N Gensous, X Demant… - Respiratory …, 2024 - Springer
Background Infliximab is currently recommended as a third-line treatment for refractory
sarcoidosis. Data in function of clinical phenotype are currently lacking. We evaluated …

Innate and adaptive immunity in noninfectious granulomatous lung disease

AS McKee, SM Atif, MT Falta… - The Journal of …, 2022 - journals.aai.org
Sarcoidosis and chronic beryllium disease are noninfectious lung diseases that are
characterized by the presence of noncaseating granulomatous inflammation. Chronic …

[HTML][HTML] Th17. 1 细胞与系统性红斑狼疮发病机制的研究进展

田微, 宗禹萱, 周飞, 钟威 - Advances in Clinical Medicine, 2023 - hanspub.org
系统性红斑狼疮(Systemic lupus erythematosus, SLE) 是一种慢性, 累及多系统多器官的,
自身免疫性疾病, 可致重要脏器损害, 诊断不及时或治疗不当可危及患者生命 …

Metabolomics and Transcriptomic Approach to Understand the Pathophysiology of Interstitial Lung Disease

S Dasgupta, A Bhattacharya, P Choudhury… - … Applications in Genetic …, 2023 - Springer
Interstitial lung diseases (ILD) are a heterogeneous group of parenchymal pulmonary
disorders that result from varying degrees of inflammation or fibrosis in the lung interstitium …