Calcium Regulation of Connexin Hemichannels

E Bayraktar, D Lopez-Pigozzi, M Bortolozzi - International Journal of …, 2024 - mdpi.com
Connexin hemichannels (HCs) expressed at the plasma membrane of mammalian cells are
of paramount importance for intercellular communication. In physiological conditions, HCs …

[HTML][HTML] Calcium Role in Gap Junction Channel Gating: Direct Electrostatic or Calmodulin-Mediated?

C Peracchia - International Journal of Molecular Sciences, 2024 - mdpi.com
The chemical gating of gap junction channels is mediated by cytosolic calcium (Ca2+ i) at
concentrations ([Ca2+] i) ranging from high nanomolar (nM) to low micromolar (µM) range …

A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model

A Tettey-Matey, V Donati, C Cimmino… - Cell Communication and …, 2024 - Springer
Connexins (Cxs) are fundamental in cell–cell communication, functioning as gap junction
channels (GJCs) that facilitate solute exchange between adjacent cells and as …

Pathophysiological role of connexin and pannexin hemichannels in neuromuscular disorders

W Vásquez, CA Toro, CP Cardozo… - The Journal of …, 2024 - Wiley Online Library
A growing body of research has provided evidence that de novo expression of connexin
hemichannels and upregulation of pannexin hemichannels (Cx HCs and Panx HCs …

[HTML][HTML] Connexins and Aging-Associated Respiratory Disorders: The Role in Intercellular Communications

T Zubareva, E Mironova, A Panfilova, Y Krylova… - …, 2024 - pmc.ncbi.nlm.nih.gov
This article reviews the contemporary understanding of the functional role of connexins in
intercellular communications, their involvement in maintaining cellular and tissue …