Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
Molecular dynamics simulation for all
SA Hollingsworth, RO Dror - Neuron, 2018 - cell.com
The impact of molecular dynamics (MD) simulations in molecular biology and drug discovery
has expanded dramatically in recent years. These simulations capture the behavior of …
has expanded dramatically in recent years. These simulations capture the behavior of …
Transcriptional architecture of synaptic communication delineates GABAergic neuron identity
Understanding the organizational logic of neural circuits requires deciphering the biological
basis of neuronal diversity and identity, but there is no consensus on how neuron types …
basis of neuronal diversity and identity, but there is no consensus on how neuron types …
Structural and functional architecture of AMPA-type glutamate receptors and their auxiliary proteins
IH Greger, JF Watson, SG Cull-Candy - Neuron, 2017 - cell.com
AMPA receptors (AMPARs) are tetrameric ion channels that together with other ionotropic
glutamate receptors (iGluRs), the NMDA and kainate receptors, mediate a majority of …
glutamate receptors (iGluRs), the NMDA and kainate receptors, mediate a majority of …
Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor
AMPA glutamate receptors (AMPARs), the primary mediators of excitatory
neurotransmission in the brain, are either GluA2 subunit-containing and thus Ca2+ …
neurotransmission in the brain, are either GluA2 subunit-containing and thus Ca2+ …
AMPA receptor structure and auxiliary subunits
A Kamalova, T Nakagawa - The Journal of physiology, 2021 - Wiley Online Library
Fast excitatory synaptic transmission in the mammalian brain is largely mediated by AMPA‐
type ionotropic glutamate receptors (AMPARs), which are activated by the neurotransmitter …
type ionotropic glutamate receptors (AMPARs), which are activated by the neurotransmitter …
[HTML][HTML] Activation and desensitization mechanism of AMPA receptor-TARP complex by cryo-EM
AMPA receptors mediate fast excitatory neurotransmission in the mammalian brain and
transduce the binding of presynaptically released glutamate to the opening of a …
transduce the binding of presynaptically released glutamate to the opening of a …
Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP γ8
INTRODUCTION Neuronal communication at excitatory synapses in the brain involves
release of the neurotransmitter l-glutamate from the presynapse of one cell and its detection …
release of the neurotransmitter l-glutamate from the presynapse of one cell and its detection …
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
AMPA-subtype ionotropic glutamate receptors (AMPARs) mediate fast excitatory
neurotransmission and contribute to high cognitive processes such as learning and memory …
neurotransmission and contribute to high cognitive processes such as learning and memory …
Structural bases of desensitization in AMPA receptor-auxiliary subunit complexes
Fast excitatory neurotransmission is mediated by AMPA-subtype ionotropic glutamate
receptors (AMPARs). AMPARs, localized at post-synaptic densities, are regulated by …
receptors (AMPARs). AMPARs, localized at post-synaptic densities, are regulated by …